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2004, № 10



Timoshinova S.V., Sharapova N.V., Mikhailova I.V., Krasikov S.I., Boev V.M., Smolyagin V.I. THE INFLUENCE OF CHRONICAL INTOXICATION WITH CHROME AND BENZOL ON ANTIOXIDANT STATUS OF RATS The influence of chronical intoxication with chrome and benzol on antioxidant status of rats was studied in the model experiment on rats of Wistar line. Rats got these matters with water during 45 days. The chemiluminescence indexes of experimented animals were in 1.5 higher than of animals of intact group. Chronical intoxication with potassium dichromate conducted to rise of catalysis activity and superoxide dismutase on the average in 20-40 %. At the same time, the activity of superoxide dismutase depression about in 20-30% at invariance of catalysis activity on the level of intact group was marked at benzol intoxication. Thus the conclusion about different ways of realization of pro-oxidant benzol and chrome influence was made in this article.

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Authors: Mihaylova I.V., Timoshinova S.V., Sharapova N.V., Krasikov S.I., Boev V.M., Smolyagin V.I.

Year: 2004


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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