Krasikov S.I., Tukhvatullin P.F., Timoshinova S.V.
ANTIOXIDANT ACTIVITY CHANGES OF FERMENTS AT ALCOHOLISM TREATMENT ^{[№ 5 (app.1) ' 2005]}
This research was devoted to research of chronic alcohol use influence on antioxidant organism status and dependence between changes of ferments activity of antiradical defense, happened as a result of treatment, and duration of following remission. The results of got research showed that long alcoholization gave great changes in antioxidative organism status. It was shown that in experimental group SOD activity was in general in 60 % higher, but catalase activity was in 1,8 times lower in comparison with control. The results revealed significant differences in antioxidative ferments activity before and after treatment. Remission duration depended on changes character and was maximal (on average, seven weeks) at simultaneous increase of SOD and catalase activity. Remission duration was not more than 4-5 weeks at increase of one ferment activity with simultaneous decrease of another ferment activity. Depression of all studied antioxidant ferments reduced remission term till 1-3 weeks.

Timoshinova S.V., Sharapova N.V., Mikhailova I.V., Krasikov S.I., Boev V.M., Smolyagin V.I.
THE INFLUENCE OF CHRONICAL INTOXICATION WITH CHROME AND BENZOL ON ANTIOXIDANT STATUS OF RATS ^{[№ 10 ' 2004]}
The influence of chronical intoxication with chrome and benzol on antioxidant status of rats was studied in the model experiment on rats of Wistar line. Rats got these matters with water during 45 days. The chemiluminescence indexes of experimented animals were in 1.5 higher than of animals of intact group. Chronical intoxication with potassium dichromate conducted to rise of catalysis activity and superoxide dismutase on the average in 20-40 %. At the same time, the activity of superoxide dismutase depression about in 20-30% at invariance of catalysis activity on the level of intact group was marked at benzol intoxication. Thus the conclusion about different ways of realization of pro-oxidant benzol and chrome influence was made in this article.