Vestnik On-line
Orenburg State University december 26, 2024   RU/EN
Headings of Vestnik
Pedagogics
Psychology
Other

Search
Vak
Антиплагиат
Orcid
Viniti
ЭБС Лань
Rsl
Лицензия Creative Commons

2015, № 12 (187)



Ioyleva E.E., Krivosheeva M.S. FEATURES OF VISUAL IMPAIRMENT IN FAMILIAL FORMS OF MULTIPLE SCLEROSISIt is known that the risk of developing MS in the immediate family is 10-15 times higher than in the general population. According to the researchers, when the family form at the onset of the disease is dominated by visual, oculomotor and sensory disorders. With regard to visual impairment in familial forms of MS are no reliable confirmation of concordance. To study visual impairment in familial forms of MS. 2 families in which two relatives diagnosed MS cerebrospinal form. In both cases, the manifesto of multiple sclerosis began with visual impairment. Onset of the disease was accompanied by visual disturbances with a sharp decrease in central vision, and pain. In one family at the sister (43 years), optic neuritis was observed at the age of 21, with multiple recurrences at intervals of 1 to 3 years. She noted the growth of neurological symptoms, despite treatment. The progressive course of MS led to disability at 6 years after the onset of the disease. There was a pronounced neurological deficit, reduced visual function in connection with the development of optic nerve atrophy. Brother disease is diagnosed for the first time. Both have the same clinical manifestation in the form of visual impairment prior to the neurological clinic, had the same age range debut. Also confirmed is the same form of the disease — cerebrospinal. In FGBU "Eye Microsurgery Complex" named S.N. Fedorov over the past 5 years found 2 families with MS, which amounted to 2 % of all patients with visual impairment due to MS. Revealed concordance form of the disease, the age range and the first manifesto in the immediate family. When the family form PC optic neuritis preceded by neurological symptoms.Key words: optic neuritis, visual impairment, multiple sclerosis, familial forms of multiple sclerosis.

Download
References:

1. Gusev EI, Zavalishin IA, Boiko AN, MS, clinical guidelines, M., 2011, 782 p.

2. Karnaukh VN, Barabash IA Family sclerosis // Far East Medical Journal 2009 — № 1, pp. 71-73

3. Ioyleva EE, MS Krivosheeva One-sided swelling of the optic nerve: features differential diagnosis // Tauride Medical and Biological Bulletin. — 2013. — №3. — Part 2. — S.166-170

4. Ioyleva EE, LV Sychev The diagnostic method of monocular optic neuritis as the debut of multiple sclerosis, RF patent number 2446730 on 16.11.2010

5. Ioyleva EE, Krivosheeva MS, Smirnova MA The survey of patients with optic neuritis at the onset of multiple sclerosis // Herald OSU. — 2014. — №12 — s.143-146.

6. Balcer LJ. Clinical practice: optic neuritis. N Engl J Med. 2006;354:1273–1280

7. McDonald WI, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the Diagnosis of Multiple Sclerosis. Ann Neurol. 2001;50:121–12

8. Turano K.A., Broman A.T., Bandeen-Roche K., et al. the SEE Project Team. Association of visual field loss and mobility performance in older adults: Salisbury Eye Evaluation Study — Optom. and Vis. Sci. 2004. — Vol. 81.-P. 298-307.


About this article

Authors: Ioyleva E.E., Krivosheeva M.S.

Year: 2015


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

Crossref
Cyberleninka
Doi
Europeanlibrary
Googleacademy
scienceindex
worldcat
© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru
1999–2024 © CIT OSU