Ioyleva E.E., Krivosheeva M.S.
FEATURES OF VISUAL IMPAIRMENT IN FAMILIAL FORMS OF MULTIPLE SCLEROSIS ^{[№ 12 ' 2015]}
It is known that the risk of developing MS in the immediate family is 10-15 times higher than in the general population. According to the researchers, when the family form at the onset of the disease is dominated by visual, oculomotor and sensory disorders. With regard to visual impairment in familial forms of MS are no reliable confirmation of concordance. To study visual impairment in familial forms of MS. 2 families in which two relatives diagnosed MS cerebrospinal form. In both cases, the manifesto of multiple sclerosis began with visual impairment. Onset of the disease was accompanied by visual disturbances with a sharp decrease in central vision, and pain. In one family at the sister (43 years), optic neuritis was observed at the age of 21, with multiple recurrences at intervals of 1 to 3 years. She noted the growth of neurological symptoms, despite treatment. The progressive course of MS led to disability at 6 years after the onset of the disease. There was a pronounced neurological deficit, reduced visual function in connection with the development of optic nerve atrophy. Brother disease is diagnosed for the first time. Both have the same clinical manifestation in the form of visual impairment prior to the neurological clinic, had the same age range debut. Also confirmed is the same form of the disease — cerebrospinal. In FGBU "Eye Microsurgery Complex" named S.N. Fedorov over the past 5 years found 2 families with MS, which amounted to 2 % of all patients with visual impairment due to MS. Revealed concordance form of the disease, the age range and the first manifesto in the immediate family. When the family form PC optic neuritis preceded by neurological symptoms.