Vestnik On-line
Orenburg State University december 24, 2024   RU/EN
Headings of Vestnik
Pedagogics
Psychology
Other

Search
Vak
Антиплагиат
Orcid
Viniti
ЭБС Лань
Rsl
Лицензия Creative Commons

2013, № 12 (161)



Notova S.V., Timasheva A.B., Lebedev S.V., Sizovа E.A.,Miroschnikov S.V. ELEMENT STATUS AND BIOCHEMICAL COMPOSITION OF BLOOD LABORATORY ANIMALS WHEN ADMINISTERED INTRAMUSCULARLY ASPARGINATA AND COPPER NANOPARTICLESThe paper presents the results of a study of the element status and biochemical composition of the blood of laboratory animals when copper in various forms. It was revealed that the performance of mineral metabolism depend on the physical and chemical form of the metal. Since the introduction of copper aspartate accompanied by significant increase in concentration of Co, Cu, Ca, P, Sr against decrease I, Se, Pb. At the same time the introduction of copper nanoparticles increases the concentration of Cu, Ca, P, Al, Sr, against reduction Pb and I. when introduced into the body of copper in nanoform, biochemical blood indices have lower values than in a asparginata.Key words: copper nanopowder , asparginat copper rat experiment, essential trace elements, blood biochemistry.

Download
References:

1. Klotz L., Kronche K., Buchzyk D. et al. // J. Nutr. 2003 . — Vol. 133. Suppl. — P. 1448S-1451S.

2 . Strickland G. T., Beckner W. M. // Clin. Sci. — 1972 . — Vol. 43. — P. 617-625 . Turnlund J. R., Keyes W. R., Anderson H. L. et al. // Am. J. Clin. Nutr. — 1989 . — Vol. 49. — P. 870-878 .

3 . Johnson M.A., Murphy C.L. // Am. J. Clin. Nutr. 1988 . — Vol. 47. — P. 96-101 . 25 Polberger S., Fletche M., Graham T. et al. // J. Pe-diatr. Gastroenterol. Nutr. — 1996 . — Vol. 22. — P. 134-143.

4 . Antonovich E.A. toxicity of copper and its compounds / Antonovich E.A., Podushnyak A.E., Schutskiy T.A., Institute of Ecological Hygiene and Toxicology . LI Medved . — Kyiv, 2005. — 28 sec. 2 .

5 . Vishnjakov A.I., Features of bone marrow blood with the introduction of copper nanoparticles per os and intramuscularly / Vishnjakov A.I., Ushakov A.S., Lebedev S.V. // Bulletin of beef cattle . — 2011 . — Volume 2 , № 64. — S. 96-102 .

6. Sizovа E.A., Miroschnikov S.A., Lebedev S.V., Gluschenko N.N. Effect of repeated administration of copper nanoparticles on the elemental composition of rat liver / Sizovа E.A., Miroschnikov S.A., Lebedev S.V., Gluschenko N.N. // Bulletin of the Orenburg State University , № 6 , 2012. — P. 1-3.

7. Sizovа E.A., Lebedev S.V., Polyakovа V.S., Glushchenko N.N. Structural and functional reorganization of rat spleen with intramuscular injection of copper nanoparticles type cu10x / Sizovа E.A., Lebedev S.V., Glushchenko N.N. — № 2, 2010, pp. 129-133 .

8. Theological O.A., Sizovа E.A., Polyakovа V.S, Miroschnikov S.A., Leipunsky I.O., Olkhovskaya I.P., Gluschenko N.N. Safety study of the introduction of copper nanoparticles with different physical and chemical characteristics to animals. Bulletin of the Orenburg State University. — № 2, 2009 . — S. 124-127 .

9. Glushchenko N.N., Theological O.A., Olkhovskaya I.P. // Physical and chemical laws of the biological action of fine metal powders . Chemical Physics. — 2002 . — T. 21 ( 4). — S. 79-85 .

10 Gene M.J., Miller A. USSR Certificate number 814432 . Bulletin of inventions. — 1981 . — № 11. — S. 25.3 .

11. Avtsyn A.P., Lark A., M. Risch , etc. Human microelementoses : etiology , classification, organopathology . Moscow, Medicine , 1991. — 496 s .


About this article

Authors: Miroshnikov S.V., Sizova E.A., Notova S.V., Timasheva A.B., Lebedev S.V.

Year: 2013


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

Crossref
Cyberleninka
Doi
Europeanlibrary
Googleacademy
scienceindex
worldcat
© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru
1999–2024 © CIT OSU