2012, № 1 (137)

Barkov V.N., Kochkina N.N., Severinova S.B., Grechikhina S.V., Petrenko V.L., Matchin A.A. MORPHOFUNCTIONAL ASPECTS OF STUDY OF THE IMPACT OF INFECTION ON WOUND HEALING OF MAXILLOFACIAL REGION IN THE EXPERIMENTThe authors conducted experimental pathology experiment of infection on healing of wounds of maxillofacial region performed on 40 white adult rats creating a model of fully-layered punctured wound of maxillofacial area (cheeks). Detected changes in the tissue in the zone of wound defect significantly compounded by the exogenous infection. These changes lead to fibrosis, secondary necrosis, , a lack of meaningful granulation tissue resulting in lack both histo-and organic typical, elements differentiation, process of chronic diseases. These results justify the need for correction of microbial effects on tissue of maxillofacial area with cross-cutting injuries. Key words: wound of maxillofacial area, reparative histogenesis, wound infection.

Download

References:

1. Artamonov O.G., Bogoutdinov Z.A., Namokonov E.V. Antioxidant stimulation of reparative processes in a wound // Morphologicheskie vedomosti. — М., 2009. — No.3. — P. 163-164.

2. Belyaev A.N., Rigin A.N., Zakhvatov A.N. Systemic and regional antioxidant therapy at complicated forms of diabetic foot. // Surgery. — 2007. — No.11. — P. 46-50.

3. Gusev E.Yu., Yurchenko L.N. Systemic inflammation as typical pathological process // Cytokines and inflammation. — 2004. — Т.3, No.3. — P. 48-53.

4. Davydovskiy I.V. Firearm wound of a man. — М.: АМN SSSR, 1952. — T.1. — 468 p.

5. Korepanova O.A. Effect of bacterial lipopolyssacharide introduction on the activity of tanicytal glia of the third ventricle of rat cerebrum. — М.: RAEN, 2007. — 146 p.

6. Kuzin M.I., Kostyuchenok M.I. Wounds and wound infection: guidance for doctors. — М.: Meditsina, 1990. — 592 p.

7. Limberg Al.A. Actual problems of organization of medical aid to patients with concomitant craniocerebral injury / Progressive technologies at the turn of the century. — М, 2000. — 50 p.

8. Stadnikov A.A. Стадников А. А. Hypothalamic factors of growth processes regulation, proliferation and cytodifferentiation of adenohypophysis epithelium. — Ekaterinburg: UroRAN. — 1999. — 137 p.

9. Titova A.T. Improvement ways of specialized help organization at face injuries in patients with concomitant and multiple trauma// Treatment of face injuries in patients with multiple and concomitant trauma. — L.: — 1986. — P. 4-7.

10. Trunin D.A. Trauma of face medium zone. — Moscow: ОАО Stomatology. — SamGMU: — 2001. — P. 18

11. Selinfreund R.H. Insulin-like growth factor-I induces a rapid increase in calcium currents and spontaneous membrane activity in clonal pituitary cells. — American Society for Pharmacology and Experimental Therapeutics. — 2001. — Issue 6. — Р. 1215-1220.

About this article

Authors: Grechihina S.V., Barkov V.N., Kochkina N.N., Severinova S.B., Petrenko V.L., Matchin A.A.

Year: 2012

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru