Kochkina E.E., Pashkova T.M., Sycheva M.V., Kartashova O.L.
CHARACTERISTICOF BACTERIA OF THE GENUS ENTEROCOCCUS BIOPROFILES ISOLATED FROM ANIMALS ^{[№ 9 ' 2017]}
The increasing clinical significance of enterococci highlights the issue of the safety of their use as anti-infective biologics probiotic and requires the search algorithm for the effective differentiation of clinically significant strains from representatives metallisticheskoy microbiota.
Studied the biological properties of bacteria of the genus Enterococcus isolated from the feces of clinically healthy productive animals and from animals with infectious and inflammatory diseases. Determined bioprofile characterizing pathogenic and non-pathogenic isolates. In addition to the genetic determinants of the virulence factors of the strains isolated in the pathology detected hemolytic, gelatinase activity and the factors of persistence (ALA, Acre), with higher characteristic values than fecal cultures. Strains isolated from the intestines of healthy animals was characterized by a high activity of proteases and not had the ability to form biofilm.
The obtained results can be used for differentiation of pathogenic variants Enterococcus spp. from symbiotic cultures included in the composition of the intestinal normality.

Barkov V.N., Kochkina N.N., Severinova S.B., Grechikhina S.V., Petrenko V.L., Matchin A.A.
MORPHOFUNCTIONAL ASPECTS OF STUDY OF THE IMPACT OF INFECTION ON WOUND HEALING OF MAXILLOFACIAL REGION IN THE EXPERIMENT ^{[№ 1 ' 2012]}
The authors conducted experimental pathology experiment of infection on healing of wounds of maxillofacial region performed on 40 white adult rats creating a model of fully-layered punctured wound of maxillofacial area (cheeks). Detected changes in the tissue in the zone of wound defect significantly compounded by the exogenous infection. These changes lead to fibrosis, secondary necrosis, , a lack of meaningful granulation tissue resulting in lack both histo-and organic typical, elements differentiation, process of chronic diseases. These results justify the need for correction of microbial effects on tissue of maxillofacial area with cross-cutting injuries.