Barkov V.N., Kochkina N.N., Severinova S.B., Grechikhina S.V., Petrenko V.L., Matchin A.A.
MORPHOFUNCTIONAL ASPECTS OF STUDY OF THE IMPACT OF INFECTION ON WOUND HEALING OF MAXILLOFACIAL REGION IN THE EXPERIMENT ^{[№ 1 ' 2012]}
The authors conducted experimental pathology experiment of infection on healing of wounds of maxillofacial region performed on 40 white adult rats creating a model of fully-layered punctured wound of maxillofacial area (cheeks). Detected changes in the tissue in the zone of wound defect significantly compounded by the exogenous infection. These changes lead to fibrosis, secondary necrosis, , a lack of meaningful granulation tissue resulting in lack both histo-and organic typical, elements differentiation, process of chronic diseases. These results justify the need for correction of microbial effects on tissue of maxillofacial area with cross-cutting injuries.