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2012, № 1 (137)

Volkov Yu.O., Matchin A.A., Stadnikov A.A., Mikhailova I.A., Kiriakidi S.Kh., Barkov V.N. EXPERIMENTAL-HISTOLOGICAL STUDIES OF REPARATIVE PROCESSES IN THE INJURY OF MAXILLOFACIAL AREA IN TERMS OF INFECTION (NEUROBIOLOGICAL ASPECTS) In the experiment on the created model of rat's down jaw break by impact of controlled power processes of healing in different experimental conditions were studied , including the use of oxytocin and antibiotic. On the basis of an integrated morphofunctional study of posttraumatic tissue regeneration of maxillofacial area of experimental animals for the first time the authors defined the degree of histoblastic and organotypic heteromorphy (intra-and inter-differentiation). Oxytocin (especially in combination with antibiotic) optimizes the phase of inflammation in the area of traumatic injury by helping to create a histo-organotypic regenerates, which may be an evidentiary test of wound process and its therapeutic correction.Key words: bone and soft tissue of maxillofacial area, traumatic injuries, regeneration, hypothalamus, oxytocin.


1. Avtandilov, G.G. Medical morphometry / G.G.Avtandilov// M., Meditsina, 1990.-384p.

2. Balin V.N., Aleksandrov N.M., Clinical and operative maxillofacial surgery. — SPb: "Spetsialnaya literatura", 2005. — P. 23-24.

3. Barkov, V.N. Experimental and morphological substantiation of neuropeptides and demineralised bone matrix application in treatment of patients with jaw cysts.- Author's abstract …cand. med. sciences. Orenburg, 2004. — 19p.

4. Beznosik N.V. Morphofunctional peculiarities of pulp and dentinogenesis in traumatic periodontitis conditions: Author's abstract … cand. med. sciences — Orenburg, 2010. — 25 p.

5. Kochkina N.N. Structural and functional changes of soft tissues in the aspect of neuroendocrinal regulation at penetrate hurts of buccal region (experimental and histological investigation): Author's abstract …cand. med. sciences. Orenburg, 2010. — 26 p.

6. Polenov A.L., Konstantinova M.S., Garlov P.E. Pituitary-hypothalamic neuroendocrinal complex // Neuroendocrinology. SPb., 1994. T.2.- P.139-286.

7. Serov V.V., Paukov V.S. Inflammation. — М.: Meditsina. — 1995. — 640 p.

8. Stadnikov A.A. The role of hypothalamic neuropeptides in interaction of pro- and eukarya. Structural and functional aspects. — Ekaterinburg: — 2001. — P. 171-198.

9.Shargorodskiy A.G. Traumas of soft tissues and face bones. / М.: Publishing house "GEOTAR-MED". — 2004. — P. 3-7.

About this article

Authors: Kiriakidi S.H., Mihaylova I.A., Volkov Yu.O., Matchin A.A., Stadnikov A.A., Barkov V.N.

Year: 2012

Sergey Aleksandrovich

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