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Letuta S.N., Nikiyan A.N., Davidova O.K. RODOMINE STAINS AND DNA INTERACTION. The article deals with the investigation of rodamine stains and DNA interaction by means of spectrophotometric methods and probe scanning microscopy. If was shown that rodamines interact with macromolecules by cooperative fixation with the external past of polymeric chain. As a result organic nanostructures (supramolecular systems) are formed on the polymer surface. The stain molecule quantify is estimated. The distribution of generated structures along the double DNA spiral and their fusion in larger conglomerates are investigated. The authors draw a conclusion about double spiral screening by means of stains and the nucleinic acids inactivation resulting in violations of their biological functions.
About this article
Authors: Davydova O.K., Letuta S.N., Nikiyan A.N.
Year: 2001
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Editor-in-chief |
Sergey Aleksandrovich
MIROSHNIKOV |
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