Averchenkova E., Averchenkov A., Kulagina N., Aksenenko D.
THE MODEL ASSESSING THE POTENTIAL OF CREATION AND DEVELOPMENT OF CLUSTER AGGLOMERATION IN THE INDUSTRIAL COMPLEX OF BRYANSK REGION ^{[№ 8 ' 2015]}
The article describes the features for creation the cluster agglomerations in the Bryansk region in the framework of the Strategy of innovation development of Russian Federation for the period till 2020. There is algorithm for the assessment of possibility for creation and development the cluster agglomeration in machine building industry of Bryansk region. In accordant with it, the region is considered as a social economic system. It has interconnected-governmental and interacting components, and the relationships between them in a changing environment. On the basis of a mathematical model of cooperation regional social economic system with the internal environment, and classification model of the indicators, defining innovative sub sectors of machine-building complex in the Bryansk region, it was formed multivariate model, which determines the position of sub sectors of machine-building complex in the Bryansk region in point of view the making of cluster agglomeration. The work result is the creation of the priorities list for the region cluster agglomeration formation. So, it was proposed the model of information advising system of the evaluation and diagnostic type. The main goal of the proposed information advising system is constant observing over the cluster functioning, identifying positive and negative trends of changing regional social and economic system and it's environment. The output system parameters are increasing the quality of the managerial decisions in clustered agglomerations.

Valeyeva L.A., Kulagina I.G., Yafayeva E.G.
THE EFFECT OF DIAZEPAM ON MOTION ACTIVITY OF RATS DEPENDING ON THE CIRCADIAN TIME AND DENSITY OF CEREBRAL GABA RECEPTORS ^{[№ 6 ' 2014]}
The effect of diazepam on motion activity in rats after morning and evening introduction has been studied. It has been found that maximal suppressing effect of the medecation on the motion coefficient in a test "open area" is observed after evening introduction at the highest density of cerebral GABA receptors. After morning injection the suppressing effect is observed twice, i.e. immediately after the injection and during evening hours against the background of receptor increase.

Kulagina T.I.
THEMODELOFTHEDEVELOPMENTOF COGNITIVE INDEPENDENCE OF STUDENTS OF ECONOMIC SPECIALITIESIN LEARNING OF A FOREIGN LANGUAGE ^{[№ 11 ' 2013]}
The structure and content of a model of cognitive autonomy of students of economic specialitiesin learning a foreign languageis definedas the one built on integrity, completeness, consistency,interconditionality and interdependence of its components: the laws and principles, stages, goals, content, methods, forms and results, ie. didactic system that ensures the development of cognitive independence.

Ushakova Yu.V., Kulagina E.P., Chepasov V.I.
DETERMINATION OF IGF-1 AND LEPTIN IN BLOOD SERUM OF PATIENTS WITH PANCREATIC DIABETES AND DIABETIC NEPHROPATHY AND DEVELOPMENT OF METHODS FOR IDENTIFICATION OF GROUPS OF PATIENTS WITH DN ^{[№ 9 ' 2009]}
Target of examination was study of level of serum IGF-1 and leptin of patients with diabetic nephropathy (DN) and development of the methods which would allow to prognose rates of IGF-1 and leptin of children with DN and identify the group of patients with unknown pathology. 24 children 3-18 years aged (average age 14,78 years{95% DN: 13,52-16,04}) have been examined. Clinico-laboratory figures, rates of concentration of IGF-1 and leptin in blood serum have been valuated. They used multivariate statistics methods (correlation analysis, factor analysis and regression analysis) to detect patterns of relationship between main rates of the examined group. As to children with DN, their serum IGF-1 concentration is determined by the age of a patient at the moment of investigation; index of interlobar renal arteries pulsation; decrease of passing rate of radiopharmaceutical through bloodstream by left kidney; time of getting maximum in left kidney. The level of serum leptin of children belonging to the investigated group is characterized by a relative insulin dose of short effect.

Kulagina E.P., Ushakova Yu.V., Chepasov V.I.
WORKING OUT OF METHODS OF SERUM IFR-1 AND LEPTINE LEVEL DETERMINATION OF PATIENTS WITH PANCREATIC INSULAR DIABETES WITHOUT DIABETIC NEPHROPATHY ON THE BASE OF MULTIVARIATE STATISTICS METHODS ^{[№ 5 ' 2009]}
In this article the authors show the method of IFR-1 and leptine indexes determination in a blood serum of children with pancreatic insular diabetes without diabetic nephropathy with help of which it is possible to set their optimal level and to distinguish the patients who are not threatened with diabetic nephropathy development. On the base of multivariate statistics method the model for IFR-1 indexes and leptine forecasting in a blood serum of patients with pancreatic insular diabetes without diabetic nephropathy and identification of group of patients with pancreatic insular diabetes without diabetic nephropathy.

Kulagina T.I.
DIDACTIC CONDITIONS OF COGNITIVE INDEPENDENCE DEVELOPMENT OF ECONOMIC SPECIALTIES STUDENTS AT THE PROCESS OF FOREIGN LANGUAGE TEACHING ^{[№ 6 ' 2006]}
Evolution of cognitive independence formation as personal education and dynamics of subjective-subjective relations, developed depending on cognitive independence of students, who determine its development themselves are regarded in this article. Didactic conditions of cognitive independence development of economic specialties students at the process of foreign language teaching are characterized here.

Kulagina S.G.
CULTURAL ASPECTS OF PERSON EDUCATION AND INTERCULTURAL COMMUNICATION ^{[№ 3 ' 1999]}
The aim of this paper is to discuss the language role in the cross-cultural education of an individual, interconnection of culture and universal, human mission of education in widening the knowledge about the world and for self - actualization.