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September 2015, № 9 (184)



Aptikeeva R.F., Sharapova N.V., Kovalyova F.F. THE ANTIOXIDANT STATUS AND INDICATORS OF VEGETATIVE BALANCE OF PATIENTS WITH ALCOHOLISM DEPENDING ON APPLICATION OF A COURSE OF ADAPTATION TO A PERIODIC NORMOBARICHESKY HYPOXIAAccording to static data the number of alcoholics in Russia will amount to 5 000 000 people, 3.4 % of all population. Alcohol caused death by 33 % of menhood and by 15 % women, that is to say 500 000 people per year. In spite of the sufficiently progress in dipsomania treatment that is difficult to value the efficiency of taking medical measures and to prognosis the remission periode. In consideration of impotant role of oxidant stress in development of the addiction to the ethanol, it is essential question relating to research of new actions directed to increase the power of the antioxidant systems and to restriction of oxidant stress in the complex treatment of the people with the alcohol addiction syndrom. The object of this research is to determine the expedience of the use the adoptation to the circulating hypoxia of alcohol addicted patients treatment. Under the influence of adoptation to circulating normabaristic hypoxia the process lipoids perioxide by alcohol addicted patients returned to normal after holding the adoptation's course. The adoptation to the circulating normobaristic hypoxia favoured to increase of the power of the antioxidant systems. Thus, the results of the research denote, that the adoptation to circulating normobaristic hypoxia has an essentially influence on the character of the remission and the somastic condition. The valuable contribution of the adaptative therapy consists in the complete rejection from the ethonol both in the ordinary life's situations and in cases reminding the alcohol use. It allows to improve significantly a modern complex of actions directed to the dipsomania treatment and recommemd the course of the adoptation to circulating normobaristic hypoxia for its.Key words: alcoholism, oxidizing stress, adaptation, periodic normobarichesky hypoxia.

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References:

1. Кrasikov S.I., Removal the liver and heart disease with help of the adoptation to circulating hypoxia by chronic alcoholic animals // Cardiology. — 1992. — vol. 32, 11. -P. 77-82.

2. Metelitsa D.J., Oxygen activization by enzymatic systems / M., Science. 1982. — 256 p.

3. Podymova S.D., Pathogenesis role of the essential phospholipids in the therapy of chronic alcoholic liver disease / S.D. Podymova // Gastroenterology: popular-scientific magazine. M., 2001, March. -3. P. 34-42.

4. Sirota T.V., The new approach in analysis of process adrenaline's activity and its use for measuring acrivity if superoxidesmutase / T.V. Sirota // Questions of medical chemistry. 1999.3.

5. Shulpekova I.O., The essential phospholipds in the therapy of liver disease / I.O. Shylpekova // Russian medical magazine: M., 2001, April. — 4. — P. 56-63.

6. Panchenko L. F., Oxidant stress in alcoholic liver disease / L.F. Panchenko // Biomedical chemistry. — 2013. — Vol. 59. — 4. — P. 452-458.

7. Koshkina E.A., Dipsomania and narcotism rate in Russian Federation. The manual for psychiatrist expert in narcology. Minustry of Public Health if the Russian Federation. Research Institute. M., 2000.

8. Koshkina E.A., Prevalence of narcotic means and psychotropic substances among childern and teenagers in Russian Federation. Preventing alcoholism and narcomania among youth // M., — 2000. P. 10-24.

9. Meerson F.Z., Adaptive medicine: mechanism's and protective effects of adoptation: M., Science. 1993. — 331p.

10. Meerson F.Z., Adoptation to the circulating hypoxia in therapy and rehabilutation. M., Science. 1989.

11. Moiseev V.S., Dipsomanis. Organ failure. 2014. -480 p.

12. Dicer E., NADF — dependent generation of reactive oxygen species by microsomes in the presence ofiron and redox cyclin agents / E. Dicer, A.I. Ceberbaum // Biochem. Pharmacol.-[s.l.], 1991. vol.42. № 3.-P. 529-535.

13. Gordon E., The effect of chronic etahanol consumption on pathways of ethanol metabolism / E. Gordon, S. Matsuraki, C.S. Lieber //Alcoholism.-[s.l.], 1979. –vol.3.-№ 3.-P.575-579.

14. Halsted C.H., Folate deficiency in chronic alcoholic liver disease / C.H. Halsted // New Era Global Harmony Nutr.-Seul,1989.-P.465-468.

15. Cederbaum A.I., Microsomal generation of reactive oxygen species and their possible role in alcohol hepatotoxity / A.I. Cederbaum // Alcohol. Alcohol. Suppl. — 1991.-[s.l.],1991. — vol.1. № 6. — P291-296.

16. Zuck H., In methods of enzymatic analysis / H. Zuck, H. Bergmeger — Pergamon Press. — 1963.-P. 885-894.

17. Morimoto M., Role cytochrome P4502E1 in alcoholic liver disease pathogenesis / M. Morimoto, A.L. Hagbjork, A.A. Nanji // Alcohol.-[s.l.],1993/-vol.10.-№ 6.-P.459-464.


About this article

Authors: Aptikeeva R.F., Sharapova N.V., Kovalyova F.F.

Year: 2015


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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