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2013, № 12 (161)



Notova S.V., Timasheva A.B., Lebedev S.V., Sizovа E.A.,Miroschnikov S.V. ELEMENT STATUS AND BIOCHEMICAL COMPOSITION OF BLOOD LABORATORY ANIMALS WHEN ADMINISTERED INTRAMUSCULARLY ASPARGINATA AND COPPER NANOPARTICLESThe paper presents the results of a study of the element status and biochemical composition of the blood of laboratory animals when copper in various forms. It was revealed that the performance of mineral metabolism depend on the physical and chemical form of the metal. Since the introduction of copper aspartate accompanied by significant increase in concentration of Co, Cu, Ca, P, Sr against decrease I, Se, Pb. At the same time the introduction of copper nanoparticles increases the concentration of Cu, Ca, P, Al, Sr, against reduction Pb and I. when introduced into the body of copper in nanoform, biochemical blood indices have lower values than in a asparginata.Key words: copper nanopowder , asparginat copper rat experiment, essential trace elements, blood biochemistry.

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1. Klotz L., Kronche K., Buchzyk D. et al. // J. Nutr. 2003 . — Vol. 133. Suppl. — P. 1448S-1451S.

2 . Strickland G. T., Beckner W. M. // Clin. Sci. — 1972 . — Vol. 43. — P. 617-625 . Turnlund J. R., Keyes W. R., Anderson H. L. et al. // Am. J. Clin. Nutr. — 1989 . — Vol. 49. — P. 870-878 .

3 . Johnson M.A., Murphy C.L. // Am. J. Clin. Nutr. 1988 . — Vol. 47. — P. 96-101 . 25 Polberger S., Fletche M., Graham T. et al. // J. Pe-diatr. Gastroenterol. Nutr. — 1996 . — Vol. 22. — P. 134-143.

4 . Antonovich E.A. toxicity of copper and its compounds / Antonovich E.A., Podushnyak A.E., Schutskiy T.A., Institute of Ecological Hygiene and Toxicology . LI Medved . — Kyiv, 2005. — 28 sec. 2 .

5 . Vishnjakov A.I., Features of bone marrow blood with the introduction of copper nanoparticles per os and intramuscularly / Vishnjakov A.I., Ushakov A.S., Lebedev S.V. // Bulletin of beef cattle . — 2011 . — Volume 2 , № 64. — S. 96-102 .

6. Sizovа E.A., Miroschnikov S.A., Lebedev S.V., Gluschenko N.N. Effect of repeated administration of copper nanoparticles on the elemental composition of rat liver / Sizovа E.A., Miroschnikov S.A., Lebedev S.V., Gluschenko N.N. // Bulletin of the Orenburg State University , № 6 , 2012. — P. 1-3.

7. Sizovа E.A., Lebedev S.V., Polyakovа V.S., Glushchenko N.N. Structural and functional reorganization of rat spleen with intramuscular injection of copper nanoparticles type cu10x / Sizovа E.A., Lebedev S.V., Glushchenko N.N. — № 2, 2010, pp. 129-133 .

8. Theological O.A., Sizovа E.A., Polyakovа V.S, Miroschnikov S.A., Leipunsky I.O., Olkhovskaya I.P., Gluschenko N.N. Safety study of the introduction of copper nanoparticles with different physical and chemical characteristics to animals. Bulletin of the Orenburg State University. — № 2, 2009 . — S. 124-127 .

9. Glushchenko N.N., Theological O.A., Olkhovskaya I.P. // Physical and chemical laws of the biological action of fine metal powders . Chemical Physics. — 2002 . — T. 21 ( 4). — S. 79-85 .

10 Gene M.J., Miller A. USSR Certificate number 814432 . Bulletin of inventions. — 1981 . — № 11. — S. 25.3 .

11. Avtsyn A.P., Lark A., M. Risch , etc. Human microelementoses : etiology , classification, organopathology . Moscow, Medicine , 1991. — 496 s .


About this article

Authors: Miroshnikov S.V., Sizova E.A., Notova S.V., Timasheva A.B., Lebedev S.V.

Year: 2013


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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