Vestnik On-line
Orenburg State University november 05, 2024   RU/EN
Headings of Vestnik
Pedagogics
Psychology
Other

Search
Vak
Антиплагиат
Orcid
Viniti
ЭБС Лань
Rsl
Лицензия Creative Commons

2009, № 12



Romanenko N.A., Terekhova M.S., Deryabin ALKYLXYBENZOLS INFLUENCE ON FUNCTIONAL ACTIVITY OF FC-FRAGMENTS OF ANTIBODIESAbility of alkylxybenzols (AOB) change the functional activity of Fc-fragments of antibodies responsible for the initiation of the classical wais of complement activation is studied in the system of complementdependent hemolysis. It is determined that in such system C6-AOB and C12-AOB but not in C1-AOB and C3-AOB have their own haemolytic effect in high concentrations. At lower concentrations C6-AOB and C12-AOB influence on the kinetic characteristics of reaction of complementdependent hemolysis causing a time increase of lysis coming of 50% target cells without changing of lytic reaction speed. Key words: antibodies, alkylxybenzols, Fc-fragments, complement, hemolysis.

Download
References:

1. Kozubek A., Tyman J.H.P. Resorcinolic lipids, the natural non-isoprenoid phenolic amphiphiles and their biological activity / / Chem.Rev. 1999. V. 99. No. 1. Pp. 1-31.

2. Davydova D.C., Deryabin D.G., Nikia A., El-Registan GI On the mechanisms of interaction of DNA with chemical analogues of microbial autoinducers anabiosis / / Microbiology. 2005. T. 74. № 5. S. 616-625.

3. Vostroknutova G.N., Kaprelyants A.S., Svetlichnyi V.A., El-Registan, G.I., Shevtsov V.V., Ostrokovsky D.N. Membranoaktivnye properties of the drug from the culture fluid of bacteria possessing the autoregulatory action / / Applied Biochemistry and Microbiology. 1983. T. 19. № 4. S. 547-551.

4. Peter A., Deryabin D.G., Loiko N.G., Mikhailenko N.A., Kobzeva T.F., Kanaev P.A., Nikolaev Y.A., Krupyansky Yu. F., Kozlov A.N., El-Registan G.I. Regulation alkylhydroxybenzenes functional activity of lysozyme / / Microbiology. 2009. T. 78. № 2. S. 176-185.

5. Cossack J.A., Nikolaeva N.V., Linden V.V., Shushpanov O.N. Influence alkylhydroxybenzenes some immunological reactions in vitro / / Palliative medicine and rehabilitation. 2005. № 1. 68.

6. Shushpanov O.M. Score immunotropic activity alkylhydroxybenzenes Proceedings of the XV International Scientific Conference of students, graduate students and young scientists "Lomonosov". 2008. C. 46.

7. Deryabin D.G., Romanenko N.A., El-Registan G.I. Effect on antigen-binding capacity alkylhydroxybenzenes antibody / Microbiology. 2009. T. 78. № 5. S. 569-574.

8. Wolfhound Y.A. Determination of anticomplementary activity of bacteria on the kinetics of immune hemolysis / / Bulletin of OSU. 2005. № 12. S. 51-54.

9. Linko A.M., Adlercreutz H. Whole-grain rye and wheat alkylresorcinols are incorporated into human erythrocyte membranes / / British Journal of Nutrition. 2005. V. 93. No. 1. Pp. 10-13.


About this article

Authors: Deryabin D.G., Terehova M.S., Romanenko N.A.

Year: 2009


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

Crossref
Cyberleninka
Doi
Europeanlibrary
Googleacademy
scienceindex
worldcat
© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru
1999–2024 © CIT OSU