June 2017, № 7 (207), pages 74-78

doi: 10.25198/1814-6457-207-74

Davydova О.К., Nikiyan Н.N. 1,3-DIHYDROXY-4-HEXYLRESORCINOL INCREASES BACTERIAL CELLS SENSITIVITY TO DAMAGING ACTION OF CARBON NANOMATERIALSThe relevance of disinfecting of objects of the environment is defined by need of interruption of the main ways of bacterial infections transfer. To achieve this goal, non-reagent (physical) and reagent (chemical) methods are currently used. At the same time the first ones generally include ultraviolet treatment, and the second ones —treatment with oxidants or specially selected chemical compounds. However, over time, microorganisms develop protective mechanisms for such damaging effects, so it seems possible to sensitize (increase the sensitivity) bacterial cells to already known disinfectants, and to develop new disinfectants that realize previously unknown mechanisms of antibacterial activity. In presented work increase in sensitivity of bacterial cells to damaging action of carbon nanomaterials (fullerenes and carbon nanotubes) by use of 1,3-dihydroxy-4-hexylbenzene is shown. Its action on bacterial cells significantly increases their surface affinity, strengthening of the subsequent influence of carbon nanodisinfectants and facilitating the removal of aggregates of bacterial cells and the nanocarbon particles acting on them from the media to be purified. The experimental studies form a basis for development of innovative nanodisinfectants and their compositions interesting for practical use in a disinfectology, sanitation and hygiene. Key words: bacterial cells sensitization, Escherichia coli, 1,3-dihydroxy-4-hexylbenzene, carbon nanomaterials, fullerene derivatives, carbon nanotubes, disinfection, antimicrobic action.

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About this article

Authors: Davydova O.K., Nikiyan A.N.

Year: 2017

doi: 10.25198/1814-6457-207-74

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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