October 2015, № 10 (185)

Drozdova E.A., Аleshina Е.S. ANTAGONISTIC ACTIVITY OF STRAINS PROBIOTIC PREPARATIONS AGAINST TEST ORGANISM SALMONELLA ENTERITIDIS AND EFFICIENCY OF THEIR JOINT USE WITH ANTIBIOTICS WAS DETECTEDThe result of the experiments was determined by antibiotic resistance and antagonistic activity of the strains entering into probiotic preparations in respect of the test organism Salmonella enteritidis and their possible combined action with antibiotics. The experiment was set in conditions in vitro. Against the background of antibiotic therapy in the treatment of various infections develop microecological bowel disorders such as dysbiosis. For the treatment of the effects of the most studied direction at the present time is the use of probiotics — biological drugs based on representatives of the normal microflora of man. The feasibility of the simultaneous application of probiotics most used in clinical practice, antibiotics are currently the subject of discussion, as probiotic microorganisms are sensitive to many antimicrobial agents. In this regard, we have conducted the following studies and research to substantiate the effectiveness of the joint application of probiotics based nonsporeforming bacteria with antibiotics in the treatment of Salmonella infection in in vitro.Key words: microflora, probiotics, antibiotics, test organism Salmonella enteritidis, antibiotic productivity, antibiotic resistance, antagonism, synergism, an additive effect.

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About this article

Authors: Aleshina E.S., Drozdova E.A.

Year: 2015

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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