Vestnik On-line
Orenburg State University december 24, 2024   RU/EN
Headings of Vestnik
Pedagogics
Psychology
Other

Search
Vak
Антиплагиат
Orcid
Viniti
ЭБС Лань
Rsl
Лицензия Creative Commons

March 2015, № 3 (178)



Bukharin O.V., Chelpachenko O.E., Perunova N.B., Ivanova E.V., Andryuschenko S.V. EXPERIMENTAL AND CLINICAL BASIS OF SELECTION BY ANTIMYCOTIC PHYTODRUGS The use of antilysozyme and lipolytic activity as biotarget allowed to select herbs with maximum inhibitory effect of biological properties C.albicans: Artemisia absinthium L., Rosa cinnamomea L. infusions and Juniperus communis L., Citrus limon burm., Dianthus, Melissa officinalis Chaix. и Aloe arborescens mill aromatic substances. Conducted clinical laboratory studies have shown the efficacy of selected herbal drugs, which manifestated by reducing the frequency of intestinal dysbiosis with C.albicans hypercolonization by patients with CTD and decrease frequency somatic diseases in research group,and proved the possibility of using this method of selection antimycotic drugs.Key words: Candida, antilysozyme activity, lipolytic activity, herbs.

Download
References:

1. Andreev V.A., Moskalev A.V., Sboichakov V.B., ed. Medical mycology: a guide. M.: GEOTAR-Media; 2008 — P.10-15.

2. Akhmetov S.B., Akhmetov N.T., Koteneva E.N., Adekenov S.M., Ryazantsev O.G. Promising anti-fungal properties of ether oils extracted from some species of flora Kazakhstan // Problems of medical mycology. — 2013. — V.2. — P.55.

3. Cowan M.M. Plant products as antimicrobial agents // Clinical microbiology reviews. — 1999. — V.12. — №4. — Р.564-82.

4. Prabuseenivasan S., Jayakumar M., Ignacimuthu S. In vitro antibacterial activity of some plant essential oils // BMC Complementary and alternative medicine. — 2006. — V.6. — №39. — Р.156-61.

5. Lisovskaya S.A. et al. Adhesion and resistance as criteria for evaluating the pathogenic potential clinical strains of Candida albicans // Problems of medical mycology. — 2009. — №2. — P.91-92.

6. Naglik J. et al. Candida albicans proteinases and host pathogen interactions // Cell Microbiol. — 2004. — V.6. — №10. — P.915-26.

7. Staniszewka M. et al. Virulence factors of Candida albicans // Pizegl. Epidemiol. — 2012. — V.66. — №4. — P.629-33.

8. Bramono K. et al. Comparison of proteinase, lipase and alpha-glucosidase activities from the clinical isolates of Candida species // Jpn. J. Infect Dis. — 2006. — V.59. — №2. — P.73-76.

9. Wu T. et al. Inhibition of growth and secreted aspartyl proteinase production in Candida albicans by lysozyme // J. Med Microbiol. — 1999. — V.48. — №8. — P.721-30.

10. Bukharin O.V. et al. Symbiosis and its role in infection // Ekaterinburg, Ural Branch of the Russian Academy of Sciences. — 2011. — 301 p.

11. Bukharin O.V. Persistence of pathogenic bacteria // M.: Medicine. — 1999. — 365 p.

12. Slifkin M. Tween 80 capacity test responses of various Candida species // J. Clin. Microbiol. — 2000. — V.38. — №12. — Р.4626-28.

13. Sokolov S.Y. Handbook of Medicinal Plants. M.: Medicine. — 1984. — P. 259-64.

14. Sumenko V.V. Undifferentiated connective tissue dysplasia syndrome in populations in children and adolescents // Dis. cand. honey. Sciences. Orenburg. — 2000.

15. Chelpachenko O.E. Microbiocenosis pathogenetic significance in children with bowel syn-drome connective tissue dysplasia and possible correction // Dis. Doctor. honey. Sciences. Orenburg. — 2003.

16. Lakin G.F. Biometrics. M.: Higher. wk. — 1990. — 352 p.

17. Zemtsovsky E.V. Dysplastic phenotype. Dysplastic heart. Analytical Review. SPb.: Publishing house "Olga". — 2007. — 80 p.

18. Kadurina T.I., Gorbunova V.N. Connective tissue dysplasia. St. Petersburg. — 2009. — 722 p.

19. Kartashova O.L., Utkina T.M. Regulation of persistent properties of microorganisms of various factors // Bulletin of the Orenburg Scientific Center, Ural Branch of RAS. — 2013. — №1. — http: //www.elmag.uran.ru.

20. Gardiner P. Complementary, holistic, and integrative medicine: chamomile // Pediatr Rev. — 2007. — V. 28. — P.16–8.

21. Srivastava J.K., Sanjay G.E. Characterization, Stability and Biological Activity of Flavonoids Isolated form Chamomile Flowers // Mol Cell Pharmacol. — 2009. — V.1. –№3. — Р.138.

22. Obistioiul D., Cristina R.T., Schmerold I., Chizzola R., Stolze K., Nichital I., Chiurciu V. Chemical characterization by GC-MS and in vitro activity against Candida albicans of volatile fractions prepared from Artemisia dracunculus, Artemisia abrotanum, Artemisia absinthium and Artemisia vulgaris // Chemistry Central Journal. — 2014. — V.8. — №6. — P.1-11.

23. Lu H., Zou W.X., Meng J.C., Hu J., Tan R.X. New bioactive metabolites produced by Colletotrichum sp., an endophytic fungus in Artemisia annua // Plant Sci. — 2000. — V.151. — P.67-73.

24. Samy R.P., Manikandan J., Qahtani M.A. Evaluation of aromatic plants and compounds used to fight multidrug resistant infections // Evidence — Based complementary and alternative medicine. — 2013. — V.2013. — 17p.

25. Zhang Y., Muend S., Rao R. Dysregulation of ion homeostasis by antifungal agents // Frontiers in microbiology. — 2012. — V.3. — №10. — P.3389-95.

26. Thormar H. Antibacterial and antifungal activities of essential oils // Lipids and essential oils as antimicrobial agents. — 2011. — V.12. — P.256-93.


About this article

Authors: Buharin O.V., Chelpachenko O.E., Perunova N.B., Ivanova E.V.

Year: 2015


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

Crossref
Cyberleninka
Doi
Europeanlibrary
Googleacademy
scienceindex
worldcat
© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru
1999–2024 © CIT OSU