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2015, № 12 (187)

Belyi Y.A., Tereshchenko A.V., Novikov S.V., Shatskikh A.V., Kolesnik S.V., Kolesnik A.I. CLINICAL AND MORPHOLOGICAL INVESTIGATION OF INTRAOCULAR SAFETY OF NEW BIODEGRADABLE IMPLANTThe purpose of researcher is clinical and morphological substantiation of biodegradable implant safety during it's anterior chamber and intravitreal injection. The research was performed on 60 (120 eyes) rabbits chinchilla. Clinical examination, electroretinography and histology with light microscopy were performed after 1, 3, 7, 14, 21, 30 days. To assess the status of intraocular structures prior to implantation and in the dynamics underwent ophthalmic examination: biomicroscopy, photographic registration of fundus images, electroretinography. The results of the study indicates the safety of the intraocular injection of unsaturated and saturated dexamethasone implants.Key words: implant, drug delivery, biodegradable polymer, dexametasone.

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About this article

Authors: Belyy Yu.A., Shatskih A.V., Tereshchenko A.V., Novikov S.V., Kolesnik S.V., Kolesnik A.I.

Year: 2015

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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