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2014, № 12 (173)



Ioyleva E.E., Krivosheeva M.S., Smirnova M.A. THE RESULTS OF THE EVALUATION OF PATIENTS WITH OPTIC NEURITIS AT THE ONSET OF MULTIPLE SCLEROSISStudied a set of diagnostic parameters in the two groups of patients with the first manifesto of optic neuritis at the onset of multiple sclerosis. 21 patients (42 eyes). Optic neuritis with ophthalmoscopically visible changes of the optic disk was combined with pronounced changes in OCT (no excavation, thickening of the retinal nerve fiber layer), the gross violations of EFI and demyelinating lesions in the optic nerve. Thinning of the layer of retinal ganglion cells was observed in all patients, as it took place at the thickening of retinal nerve fiber layer, and under normal terms RNFL. The combination of focal lesions of the optic nerve and the presence of lesions in the brain substance increases the probability of a definite diagnosis of MS.Key words: multiple sclerosis, optic neuritis, optical coherence tomography, MRI of the orbits.

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1. Ioyleva, E.E. Colorimetric and topographic features of the optic disc in demyelinating diseases / E.E. Ioyleva, N.S. Hajiyeva // Actual problems of neuro-ophthalmology: proceedings of the 10th scientific and practical use. Conf. — M., 2008. — P. 91–92.

2. Peresedova, A.V. Pathophysiological mechanisms of formation of neurological disorders in multiple sclerosis: Diss. … MD. / A.V. Peresedova. — M., 2006.

3. Gusev, E.I. Multiple sclerosis, clinical management / E.I. Gusev, I.A. Zavalishin, A.N. Boyko. — M., 2011. — P. 56–64.

4. Zavalishin, I.A. Multiple sclerosis: basic aspects of the pathogenesis / I.A. Zavalishin, M. Zakharova // Multiple sclerosis and other demyelinating diseases / Edited by Gusev E.I., Zavalishina I.A., A. Boyko. — M: Miklos, 2004. — P. 60–74.

5. Acopyan, V.S. Nanoarchitectonics of the retina in multiple sclerosis: diagnostic potential of optical coherence tomography (preliminary results) / V.S. Acopyan, A.N. Boyko // Ophthalmology. — 2011. — Vol. 8. — No 1. — P. 32–36.

6. Optical coherence tomography: a window into the mechanisms of multiple sclerosis / E.M. Frohman [et al.] // Nat Clin Pract Neurol. — 2008 — №4. — P. 664–675.

7. Balk, L.J. Current and future potential of retinal optical coherence tomography in multiple sclerosis with and without optic neuritis / L.J. Balk, A. Petzold // Вrain. — 2013. — №6. — P. 24–26.

8. Ziemssen, E. Perspectives of an innovative ophthalmological technology: optical coherence tomography (OCT) -what should be of interest to the neurologist? / E. Ziemssen, T. Ziemssen // Journal of Neurology. — 2010. — №5. — P. 45–48.


About this article

Author: Ioyleva E.E.

Year: 2014


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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