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2013, № 4 (153)



Trunov A.N., Arbeneva N.C., Gorbenko О.М., Shvayuk А.P., Obukhova O.O. IMBALANCE CYTOKINES IN THE TEAR FLUID IN PATIENTS WITH AUTOIMMUNE UVEITISStudy activity the local immunoinflammatory process in patients with autoimmune uveitis. We examined 60 patients with autoimmune uveitis (study group) not receiving basic treatment system autoimmune disease and 20 control patients. In the lacrimal fluid of patients before treatment, by enzyme immunoassay, was conducted determination of IL-17A, IL-8, IL-6, IL-4. Found that in the pathogenesis of uveitis associated with systemic autoimmune diseases, an important role is the development of local immunoinflammatory process, which is manifested in a significant increase in tear fluid of surveyed patients, concentrations of proinflammatory cytokines IL-17A, IL-8, that accompanied by increased concentrations of IL-4, IL-6, which play a significant role in the development of autoimmune response and chronic inflammatory processes in their relationship, which was confirmed data correlation analysisKey words: autoimmune uveitis, сytokines immunoinflammatory process.

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About this article

Authors: Arbenyeva N.S., Gorbenko O.M., Obuhova O.O., Shvayuk A.P., Trunov A.N.

Year: 2013


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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