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Kozminykh V.O., Goncharov V.I., Kozminykh E.N., Oborin D.B., Lomidze K.Sh., Berezin A.N. SYNTHESIS OF BILOGICALLY ACTIVE 3-INDOLYL DERIVATIVES OF QUINOXALINE AND PYRIDO[2,3-B]PYRAZINE BY REACTION OF 2-(2-OXO-1,2-DIHYDRO-3H-INDOL-3-ILYDEN)ACETATES WITH 1,2-DIAMINE CYCLOHEXANE AND 2,3-DIAMINE PYRIDINEEthers of 2-(2-oxo-1,2-dihydro-3H-indol-3-ilyden)acetic acids interact with 1,2-diamine cyclohexane or 2,3-diamine pyridine, forming with preparative yield 2-oxo-2,3-dihydro-1H-indol-3-ilderivatives of octahydroquinoxaline-2(1H)-one and pyrido[2,3-b]pyrazine-3(2H)-one possessing strong antimicrobic activity. The structure of obtained compounds determined with the help of IK, YaMR 1H spectroscopy and mass-spectroscopy methods is being discussed.
About this article
Authors: Kozminyh E.N., Kozminyh V.O., Goncharov V.I., Oborin D.B., Lomidze K.Sh., Berezin A.N.
Year: 2006
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Editor-in-chief |
Sergey Aleksandrovich
MIROSHNIKOV |
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