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Klimova T.A., Barysheva E.S., Sizentsov A.N.
ESTIMATION OF THE EFFECT OF ANIONIC IRON COMPONENTS ON BIOTOXICITY WITH RESPECT TO PROBIOTIC STRAINS [№ 8 ' 2017]
Metals have the ability to bioaccumulate. Microorganisms can extract and concentrate metals. This ability is possessed by microorganisms that are part of probiotic preparations, in particular bacteria of the genus Bacillus. It is very important that the microorganisms of the genus Bacillus, which are part of probiotic preparations, are self-antagonizing antagonists. Bacteria of the genus Bacillus, which are part of probiotic preparations, can exert an antitoxic effect, which manifests itself in the active excretion of toxic substances from the body, as well as heavy metals. The purpose of our work was to study the effect of anionic iron components on the biotoxicity of probiotic strains. Probiotic strains included probiotic preparations: B.šsubtilis 534, B.šcereus 5832, B.šsubtilis 10641, B.šamyloliquefaciens 10642, B.šamyloliquefaciens 10643. The data obtained indicate a significant biotoxicity of anionic iron components with respect to probiotic strains . The most sensitive were the action of the anionic components of ferric chloride III. B.šcereus 5832 and B.šamyloliquefaciens 10642, when exposed to the anionic components of iron (II) nitrate B.šsubtilis 10641, when exposed to the anionic components of iron (II) sulfate B.šamyloliquefaciens 10642. It was also found that high concentrations of anionic iron components have a significant toxic effect on all probiotic strains studied, which is due to the anionic component and, as a consequence, the level of dissociation of the molecules of the test compounds.

Skalny A.V., Salnikova E.V., Kwan O.V., Sizentsov A.N., Salnikov I.A.
EXAMINE THE RELATIONSHIP OF ZINC BIOACCUMULATION IN FOOD AND HUMAN ORGANISM IN THE ORENBURG REGION [№ 10 ' 2016]
The influence of essential elements of the human body and animals is by far one of the most pressing issues bioelementologii. Of particular interest are the vital chemical elements from the group of heavy metals involved in metabolic processes. Excessive intake of data elements entails the development of a variety of pathological conditions, in connection with which there is a necessity of monitoring the content of the data elements at different levels of the food chain, particularly in the geochemical provinces with high levels of these elements. In connection with this great interest is the study of the relationship of zinc bioaccumulation in food and the human body. The article presents data monitoring research content of zinc ions in foods and biosubstrates population of the Orenburg region. Study of food, indicates that in areas of the West and Central Orenburg content of zinc ions below the permissible concentrations, while in the Eastern zone of the Orenburg content of the studied elements exceeds analog values of 2.2 and 1.9 times, in Central and West zone, respectively. The study of biological substrates (hair) produced by the population of the Orenburg region are above the acceptable level of zinc ions in the hair of women living in the eastern region by 10%, which is confirmed by correlation and regression analysis, testifying to the direct correlation content of the metal in food and the human body.

Kvan O.V., Sizentsov A.N., Kataev V.J., Rusakova E.A.
INFLUENCE OFPROBIOTIC PREPARATIONSON CONTAINING TOXICELEMENT IN THE BODYLABORATORY ANIMALS [№ 6 ' 2014]
The influenceofprobioticson the contentof toxic elements inbone and muscle tissues of rats.Comparative analysis ofliquidprobiotic preparationon the basis ofBifidobacteriumlongumandsporobacterinpointed tothe advantageof the first, resulting in a more activereductionof toxic elementsinbone and muscletissues of rats.

Peshkov S.á., Sizentsov A.N.
BIOACCUMULATION OF HEAVY METALS BY MICROORGANISMS COMPRISING PROBIOTIC PREPARATIONS IN VITRO [№ 10 ' 2013]
This article presents the results of the study the bioaccumulation of heavy metals by probiotic strains of micro-organisms belonging to different genera. The data indicate a high level of sorption of lead, zinc and iron from the growth media.

Sizentsov A.N.
THE ABILITY OF MICROORGANISMS OF BACILLUS OF PROBIOTIC PREPARATIONS TO THE ELECTION OF BIOACCUMULATION OF HEAVY METALS IN VITRO [№ 10 ' 2013]
This article presents the results of a study of the selective bioaccumulation of heavy metals by probiotic strains of microorganisms of the genus Bacillus. The data indicate a high level of sorption of lead, zinc and iron from the culture media and a slight accumulation of magnesium, cobalt and cadmium.

Sizentsov A.N.
DYNAMICS OF MORPHOLOGICAL INDICATORS OF BLOOD OF MAMMALS AT TREATMENT BY PRO-BIOTIC PREPARATIONS OF INTOXICATION BY LEAD AND ZINC [№ 10 ' 2012]
In article are submitted data, applications of pro-biotic preparations testifying to efficiency on the basis of sort Bacillus bacteria at treatment of intoxications by lead and zinc on the basis of morphological and biochemical indicators of blood.

Sizentsov A.N., Ilyasova R.V.
EFFECTIVENESS OF COMBINED APPLICATION OF PROBIOTICS AND ANTIBIOTICS IN THE CONDITIONS IN VITRO [№ 12 ' 2011]
In experiments in vitro conditions has been set high antagonistic activity of probiotic bacterial strains E. coli M-17 "Colibacterin" and E. faecium "Linex" in relation to the test organisms, and the effectiveness of their combined use with antibiotics

Sizentsov A.N., Nugamanova E.M., Peshkov S.A.
IMPACT OF HEAVY METALS ON THE GROWTH OF PROBIOTIC STRAINS E. COLI M-17, E. FAECIUM, L. ACIDOPHILUS, L. BULGARICUS LB-51 AND BACTERIA OF THE GENUS BACILLUS IN THE CONDITIONS IN VITRO [№ 12 ' 2011]
In this paper was examined the stability of different probiotic strains of microorganisms to heavy metals in the conditions in vitro. The effect of heavy metals on the growth phase of microorganisms.

Fomina M. V., Kvan O. V., Sizentsov A.N.
THE ANALYSIS OF JOINT USAGE OF PROBIOTIC PREPARATIONS AND IRON WITH VARIOUS PHYSICAL AND CHEMICAL PROPERTIES IN EXPERIMENT [№ 12 ' 2011]
The results of researches of influence on dynamics of weight of probiotics are presented at the joint usage with iron (various physical and chemical properties) on experimental animals in the article. During research it was shoun that addition of a highly dispersive powder of iron promoted the greatest authentic improvement of live mass of experimental animals.


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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