Nikishova A.V., Kryvonosova E.V., Rybakova S.M.
CURATOR PARTICIPATION IN A STUDENT GROUP FORMATION ^{[№ 2 ' 2021]}
The existence of the supervising institution for many decades does not solve the problem of defining the functions of the student group supervisor, his role in the formation of the team, it remains very urgent. We have investigated the activities of a curator in higher education institutions. In the course of practical research, we found that it is significant to use in the curator's work such key positions as adaptation technologies, reducing the level of anxiety, minimizing material and housing difficulties, and time management. A survey of curators working in student groups of the first and second years revealed a number of problems: 1) the student group is still a completely immature collective, which complicates effective interaction; 2) most freshmen are not ready for new challenges, the requirements of a new schedule, and, ultimately, they find themselves in a situation of overload, which often leads to stressful situations; 3) some students have to experience pressure from parents or teachers in an effort to get good grades, to earn authority in a new student group. A survey of first and second year students showed the shortcomings of the educational process, such as incomplete awareness of students about their rights, responsibilities and opportunities provided by the new student status; the wish of freshmen to receive timely qualified assistance from a curator in their studies and resolving conflict situations, in adaptation, monitoring progress and attendance, communication with parents; insufficient implementation of the organizational function of the curator. The conducted research work gives grounds to conclude that the task of creating a team based on a student group can be solved with the successful implementation of the activities of the institution of supervision as a pedagogical system. The most productive for the learning process consequence of solving the indicated problem is an increase in the degree of trust at the level “curator — student” and, of course, directly in the student environment, which, in turn, leads to an increase in motivation for the learning process and, as a result, a decrease in indicators. for unsuccessful and expelled students.

Nikitina А.А., Kargapoltseva N.A.
CONSTRUCTIVE MODEL OF INTERACTION OF TEACHERS AND PARENTS IN THE INCLUSIVE EDUCATION SYSTEM ^{[№ 3 ' 2020]}
Since 2019, the National Education Project has been implemented on the territory of the Russian Federation. An integral part of the implementation of this project is the support of families with children. So within the framework of this issue, the federal project “Support for families with children” is being implemented. The main goal of the project is to create conditions for increasing the competence of students’ parents in teaching and raising children. Within the framework of the regional project, since 2019 in the Orenburg region on the basis of the state budgetary institution “Central psychological, medical and pedagogical commission of the Orenburg region”, the Consulting center “We are together” was created. At present, the already developed models are not effective enough (since the results of testing these models have not been provided), or these models cannot be implemented within educational organizations. When solving the problems of the lack of support specialists in educational organizations of the Orenburg region, we have developed a modern model of interaction between teachers and parents in the system of inclusive education. The proposed model is theoretically and scientifically grounded and promotes conscious and practical interaction between parents and teachers in the system of inclusive education. The model will be tested within the framework of a pilot project on the basis of the state budgetary institution “Central psychological, medical and pedagogical commission of the Orenburg region” by specialists of the Consulting center “We are together”. The model is also practically effective, since it can be used in the absence of support specialists in the educational organization. When specialists of the consulting center “We are together” implement it, the possibility of reaching the parental community will increase and, accordingly, the number of psychological and pedagogical services provided will increase.

Nikitina S.O.
THEORETICAL, ORGANIZATIONAL AND METHODICAL APPROACHES TO THE DEVELOPMENT OF MANAGEMENT COMPETENCE AND IMPROVEMENT THE EFFICIENCY OF THE EDUCATIONAL PROCESS ^{[№ 6 ' 2018]}
Vocational training issues, theoretical and organizational and methodological approaches to the management of the educational process, the end result of which is the training of competent specialists, bachelors and masters with a certain set of necessary competencies is important, since the development of both the educational cluster and the educational organization depends on this institutions) involved in the preparation of the necessary specialists in the region (country).
The current approaches to the management of the educational process need some adjustments related to changes in the educational services market, the urgent need to train specialists in the educational industry who are able to effectively carry out the educational process, manage them, and promote personal development and educational organization (educational institution).
High-quality educational service is, first of all, an effective educational process, with diagnostics at the entrance and the formation of certain competencies at the output, based on the principles of complexity, continuity, perspectivity, totality, optimality, level and reflexivity.
The conducted studies allow us to conclude that the successive approach in managing the educational process allows for the most efficient implementation of educational activities, interacting with all participants in the educational process.

Nikitin A.Y., Markova I.V., Lebedev S.V., Meshcheryakov A.G., Klychkova M.V.
INFLUENCE OF ENZYME PREPARATIONS ON THE PHYSIOLOGICAL AND PRODUCTIVE POTENTIAL OF BROILER CHICKENS ON THE BACKGROUND OF REPLACING THE GRAIN PART OF WHEAT WITH TRITICALE ^{[№ 8 ' 2017]}
It is very important in feeding birds to maximize the use of traditional feed. However, their use can adversely affect the metabolism and productivity of poultry due to the high content of anti-nutrients in them. For the best digestibility of difficult fissionable components of mixed fodders, it is expedient to use exogenous enzyme preparations. The issue of the indisputable positive effect of enzyme preparations Avizim, Natufos and Ronozym on the growth, physiological state and metabolism of broiler chickens when 15 % of wheat is replaced by 15 % triticale is studied. With the introduction of drugs decreased feed intake from 2.1 to 12.1 %, the maximum values when using Ronozym, the minimum — Avizima. A sufficiently high level of metabolic processes in the broiler organism also against the background of the introduction of the preparation Natufos and Ronozym was characterized by high indices in comparison with intact animals by 13.8–15.0 %. In studies, a feature in the digestibility of feed nutrients, expressed in a depression of digestibility of organic matter by 1.7 % in group I and maximum figures (78.61 %) when using Roozim. The detailing of the indices testifies to the marked superiority of the II and III experimental groups over the control ones, the difference in raw protein was 1.1 and 3.3 % (p ≤ 0.05), for raw fat 0, and 2.2 % (p ≤ 0, 05), respectively. The use of Avizima does not significantly affect the digestibility of the main nutrients of the feed, which puts it in the category not effective when used in the triticale diet.

Davydova О.К., Nikiyan Н.N.
1,3-DIHYDROXY-4-HEXYLRESORCINOL INCREASES BACTERIAL CELLS SENSITIVITY TO DAMAGING ACTION OF CARBON NANOMATERIALS ^{[№ 7 ' 2017]}
The relevance of disinfecting of objects of the environment is defined by need of interruption of the main ways of bacterial infections transfer. To achieve this goal, non-reagent (physical) and reagent (chemical) methods are currently used. At the same time the first ones generally include ultraviolet treatment, and the second ones —treatment with oxidants or specially selected chemical compounds. However, over time, microorganisms develop protective mechanisms for such damaging effects, so it seems possible to sensitize (increase the sensitivity) bacterial cells to already known disinfectants, and to develop new disinfectants that realize previously unknown mechanisms of antibacterial activity. In presented work increase in sensitivity of bacterial cells to damaging action of carbon nanomaterials (fullerenes and carbon nanotubes) by use of 1,3-dihydroxy-4-hexylbenzene is shown. Its action on bacterial cells significantly increases their surface affinity, strengthening of the subsequent influence of carbon nanodisinfectants and facilitating the removal of aggregates of bacterial cells and the nanocarbon particles acting on them from the media to be purified. The experimental studies form a basis for development of innovative nanodisinfectants and their compositions interesting for practical use in a disinfectology, sanitation and hygiene.

Nikulina A.V., Sereda N.V.
SCIENTIFIC REASONS FOR APPOINTMENT TO YOUNG GROWTH OF PRODUCTIVE ANIMAL BIOACTIVE ADDITIVES IN THE CONDITIONS OF THE SELENIUM-POOR REGION ^{[№ 10 ' 2016]}
As the territory of the Chuvash Republic refers to the high-risk areas of selenium deficiency, and the levels of trace element in the biological material of the population below the physiological norm, the development and introduction into production the methods of correction morphological status of man and animals selenium bio-additives is of great importance not only for modern physiology and elementology, but also for the economy of the country. The influence selenoorganic drugs: DAFS-25 and “Selenopiran” on hematological and biochemical parameters of calves of milk period, taking into account the biogeochemical features of the Chuvash Republic is studied. The authors conducted four series of scientific and economic experiments involving 80 calves-analogues. The excess number of erythrocytes (P < 0.01) and level of albumin and gamma-globulins (P < 0.05–0.001) in calves treated with DAPS-25 and “Selenopiran” is established. Growth of concentration of immunoglobulins at experimental calfs throughout researches is recorded. The intensity of lipid peroxidation was significantly higher at calfs from group of control, and activity of antioxidant system of experimental animals. In the conditions of the lowered temperatures the effect of the studied medicines was more expressed. It is proved that the calves on adaptive technology in terms of high and low temperatures on the background of the main diet with the use of DAFS-25 and “Selenopiran” had a favorable effect on the character of metabolic processes, lipid metabolism, hematological and immunological profiles of the animals. It was accompanied by a pronounced anti-stress and immunomodulatory effects. We recommend the use of these drugs in the practice of animal husbandry in the selenium-poor regions.

Sidorova M.A., Borisova E.O., Nikiforova A.S.
CONTROLLING OF THE HYDROLOGICAL REGIME OF SOIL OF THE CULTURAL LANDSCAPES RECREATIONAL PURPOSE ^{[№ 5 ' 2016]}
Currently, great attention is paid to the initiation of adaptation processes in the system "soil-plant" of the cultural landscapes recreational purpose. A model field experiment, aiming to identify patterns in the variation of the parameters of the hydrological regime of the cultural landscape of recreational purpose was carried out on umbricalbeluvisol soil of Moscow region. It was obtained a significant change in the volumetric soil moisture (θ), soil moisture reserves (MR) and availability of moisture for plants. In the average entire growing period is characterized by the growth of θ and MR in the layer 0–50 cm in comparison with control under the influence of mulching the soil with pine litter by 28 and 21 %, under the influence of "dry stream" by 6–40 % and 9–23 %, under the elements of the path network (the incremental track) by 5 and 4–9 % respectively. In rockery and decorative unsealed plots of soil, hydrological regimes were very similar, however, θ and MR was significantly reduced at 13–18 and 6–29 % in rockery and 2 and 4 % in decorative unsealed plots of soil. The hydrological regime of experience control variant in the dry conditions of vegetation period of 2014 was the most suitable for the growth of xero-mesophytic plants. The application of the proposed planning decisions and mulching opens up the possibility of creating a variety of sustainable plant communities on the same type of the original soil within the single recreational area.

Nikiyan H.N., Tatlybaeva E.B.
ATOMIC FORCE MICROSCOPYUSING IN IDENTIFICATION OF SPECIFICALLY MARKED MOLECULES AND MICROORGANISM CELLS ^{[№ 13 ' 2015]}
Identification of biological molecules and microorganisms is an important problem of the microbiology which is traditionally solved by means of the marked antibodies. However in most cases the corresponding methods are based on detection of a significant amount of the interacting molecules and don't allow to find out their distribution on a surface. One of possible solutions consists in use of a modern method of atomic force microscopy. In current work the specific complexes formedbynanodimensionallabels, containing colloidal gold or amorphous carbon on a surface of bacterial cages of S. aureus and on a surface of plastic microwell immunological plateswere found and studied by means of atomic force microscopy. Morphological characteristics and the map of distribution of the revealed complexes on the studied surfaces were established. In experiments with tags sensitivity of a method was defined and comparison with the enzyme-linked immunoassay was carried out. The received results indicate high sensitivity of the offered method and certain advantages of carbon labels in comparison with gold labels, because of their easy detection and unambiguity in identification on the received images. Identification of microorganisms in model two-component biological systems was carried out and approaches to marking of bacterial cages in complex biological mixes was developed for the directed their allocation and the subsequent studying. Thus, use of a atomic force microscope in combination with nanodimensional carbon and gold labels, allows to realize a new way of identification of single molecules and microorganisms in complex biological mixes.

Milyudin E.S., Nikolaeva G.A., Milyudin A.E.
CLINICAL AND MORPHOLOGICAL CHARACTERISTICS RETROKORNEAL MEMBRANES ^{[№ 12 ' 2015]}
A frequent cause of intra operative complications in repeat Keratoplasty is a need for reconstruction of the anterior chamber and excision retrokorneal fibrous growths. In this connection it is essential determining the type and nature of retrokorneal membranes. The goal of this study — to study the morphological structure retrokorneal growths in patients operated again on the pathological changes of the cornea. Observed 30 patients with vascular leukomas 4–5 category by classification Filatov — Bushmich who underwent re-keratoplasty. From remote systems during operation of the corneal disk retrokorneal membrane prepared histological sections that were stained by the method of Van Gieson and examined using a light microscope. In all patients during surgery removed retrokorneal membrane. Fibrotic growths in the anterior chamber or limited imperforate of the pupil — 4 patients (13 %) or were tougher membranes — in 26 patients (87 %). As a result of the morphological study excised corneas from membranes retrokorneal we identified three types. The first type retrokorneal membrane was represented as exfoliated Descemet's membrane, with a small number of endothelial cells. The second type retrokorneal membranes, characterized by a corneal epithelial ingrowth of scar or proliferation of endothelial. For the third type retrokorneal membrane characterized by loose connective tissue fibers, welded either iris or cornea, excessive growth of newly formed blood vessels, lymphocytic infiltration. Traumatic and long-existing inflammatory processes are the main causes of retrokorneal fibrin formations. The degree of severity and duration of inflammation are the determining factors for the development of one of three types retrokorneal membran.

Nikiforova E.B.
THE CLINICAL EPIDEMIOLOGICAL ANALYSIS OF DYNAMICS OF EYE INCIDENCE, DISABILITY AND THE STATIONARY OPHTHALMOLOGICAL HELP TO THE POPULATION OF THE SAMARA REGION DURING 2010–2014 YEARS ^{[№ 12 ' 2015]}
Statistical information of ocular morbidity, disability and prevalence determines the needs of the population in the eye care, which in turn is the basis of a network of ophthalmic offices, divisions, centers. The efficiency of use of hospital beds, the analysis of the organization of eye care in the outpatient level, the research of state of ophthalmologists allow you to adjust and optimize the organization of ophthalmic services in order to increase the availability of and satisfaction with public provision of eye care. There is the growth of ocular morbidity annually In the Samara region on during the reporting period, the growth was 9.8 %. The main role in this process was played by diseases such as cataract, glaucoma, retinal disease, disorders of refraction. In accordance with national trends in the structure of eye disability leading positions belong to glaucoma, degenerative myopia and diseases of the retina. At the same time the number of ophthalmologists of polyclinic decreased, accordingly the number of visits of ophthalmologist decreased also. Such discrepancy between the needs of the population in ophthalmological help and the actual delivery may cause a decrease the availability of ophthalmological help and, therefore, the growth of social tension in society. The clinical epidemiological analysis of dynamics of eye incidence during 2010-2014 years allowed to identify growth ophthalmological pathology of the population of the Samara region, primarily due to cataract, glaucoma, retinal diseases. The statistical indicators of stationary ophthalmological help in the Samara region improve annually. From year to year the number of patients treated in specialized ophthalmologic hospitals, in 5 years the number has increased by 32.5 %. The number of eye operations increased of 44.6 % at the same time. Modern technologies of surgical treatment of ophthalmological patients allow most of these patients to treat of hospital-replacement technology, which leads to significant reduction in bed-days and turnover of ophthalmological beds. Clinical and epidemiological analysis helped to develop a regional target program on improvement of ophthalmologic aid to the population of the Samara region and to identify the main activities to optimize the organization of the ophthalmological help to the population of the Samara region in order to improve its accessibility and quality.

Kallas E.V., Nikitich P.A.
CONSERVATION INFORMATION ABOUT PEDOGENESIS IN HUMUS PROFILES OF SOILS ^{[№ 10 ' 2015]}
The soil integrally reflects and records the action over time of all factors of pedogenesis in its properties and performs a global function in the biosphere — the information. One of the most reliable memory carriers is soil humus, which structure remains in the soil for a long time. The humus soil profile is a kind of "archive" that holds the encrypted information about the evolution of the environment at different stages of the soil formation. Humus profiles as carriers of "soil memory" are considered through the example of soils of the Tom-Yaya watershed. Humus profiles of grey forest soils developed in the taiga–forest-steppe ecotone, reflect the complex contrasting evolution due to the displacement of landscape boundaries in the Holocene and leading to different stages of pedogenesis — change the steppe (meadow ) of the type of soil on the forest. The steppe (meadow) soil type replacing the timber soil type is reflected in the profile as a second humus horizon sharply different in the composition of humus from up- and under-lying areas of the humus profile. In particular this layer has a high accumulation of humic acids and calcium humates, a significant decrease in fulvic acids and extension of the relation Cha:Cfa to 2 or more units, which is typical of black earth soils and meadow-chernozem type of soil formation. On chernozem (meadow-chernozem) soil types, grey forest soils were formed in the Holocene Optimum, as evidenced by radiocarbon age of humic acids (3 750 years). It is shown that humus profiles reflect the characteristics of the evolution of soil and store in their properties and structure the information about the change in environment during the period of formation of the soil body, and therefore can serve as a "tool" for the reconstruction and used for modelling the behaviour of soils in the future.

Nikiforova Kh.P.
THE SUBJECT OF JUDICIAL CONTROL OVER THE LEGALITY AND VALIDITY OF INVESTIGATIVE ACTIONS, LIMITING CONSTITUTIONAL RIGHTS AND FREEDOMS ^{[№ 3 ' 2015]}
Сontrol in the criminal court proceedings is a multifunctional criminal procedure of the judicial authority, carried out in the statutory procedural forms, aimed at implementing the constitutional definition of judicial protection. This paper considers one form of judicial control − judicial control of the legality and validity of investigative actions limiting constitutional rights and freedoms of the individual. The study concluded that the implementation of judicial control over the production of certain investigative actions is an essential issue in the protection of the rights, freedoms and legitimate interests of an individual. We offer to supplement article 165 of the Code of Criminal Procedure with paragraph 5.1 as follows: "The cases of urgency should be considered as the situations arising as a result of the need to promptly stop or prevent the commission of the crime, as well as creating the conviction of the examining magistrate and the investigator that the delay in the conduct of investigations may lead to destruction, damage, disappearance or concealment of objects having probative value in a criminal case, a change in their properties and qualities under the influence of certain persons or natural phenomena, in the absence of opportunities to ensure their safety". Part 5, Article 165 of the Code of Criminal Procedure should be reworded as follows: "In exceptional cases, when home inspection, search and seizure in the dwelling, body search and seizure of the thing pledged or deposited in the pawnshop, distraint specified in the Section 104.1 of the Criminal Code of the Russian Federation, is urgent, these investigations can be made on the basis of the examining magistrate's decision or investigator's decision without court decision. The decision of the examining magistrate and the investigator motivate the impossibility of conducting investigations in the manner prescribed by parts 1-4 of this article.(hereafter referred to as)".

Churakov T.K., Nikulin S.A., Kachanov A.B., Naumenko V.V., Zavyalov A.I.
OPTIMIZING THE USE OF CONFOCAL MICROSCOPY OF THE CORNEA IN THE SCIENTIFIC AND CLINICAL STUDIES ^{[№ 12 ' 2014]}
The paper presents the results of a study of the ultrastructure of the cornea by confocal microscopy. Given the particular interpretation of the results obtained using this diagnostic method. By the example of changes after LASIK studied the opportunities of layer-by-layer visualization of corneal tissue and prospects of application of the method of confocal microscopy in research and clinical practice.

Nikiyan H.N., Tatlybaeva E.B.
ACHIEVEMENTS AND DEVELOPMENT PROSPECTS OF ATOMIC FORCE MICROSCOPY IN MICROBIOLOGY ^{[№ 6 ' 2014]}
In this review the possibilities of atomic force microscopy in solving of microbiological problems over the last decade are considered. The main attention is paid to the achievements and successes in the field of biodetection, virology and studying the factors of biogenic and abiogenic influence on bacterial cells. Presented results show the potential of atomic force microscopy in detection and identification of single cells and molecules, investigations of mechanical and morphological properties of bacterial cells in response to different influences, as well as the study of the intermolecular and intramolecular interactions.

Nikulina J.N.
BUSINESS ROLE IN TRAINING OF YOUNG SPECIALISTS FOR INNOVATIVE ECONOMY OF THE REGION ^{[№ 4 ' 2014]}
Article is devoted to the problem gaining the increasing relevance in modern conditions when our country completely passes to-level higher education, including in the conditions of innovative development of economy: to assessment of a role of business in training and compliances of a professional standard of young specialists to requirements of the enterprises employers. Recommendations are offered about development of Provision on higher education institution interaction with the region enterprises, directed on establishment of long-term mutually advantageous partnership and effective interaction of university with employers.