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Letuta S.N., Maryakhina V.S., Pashkevich S.N., Rakhmatullin R.R. KINETICS OF DELAYED LUMINESCENCE OF MOLECULAR PROBES IN CELLS OF BIOLOGICAL TISSUEThis report addresses the kinetics of delayed fluorescence of organic dye molecules in the cells of the breast of healthy female mice pertaining to BYRB line and individuals with spontaneous malignant tumors. It discusses the mechanisms of suppression of delayed luminescence of molecules in the cells of tissues. It was experimentally shown that exogenous fluorophores are more accessible to oxygen in cells isolated from normal tissues.Key words: laser diagnostics, molecular probes, a long luminescence.
References:
1. Ermilov E.A., Markovskii O.L., Gulis I.M. Inductive-resonant triplet-triplet annigilation in solid solutions of erythrosine / / Journal of applied spectroscopy. — 1997. — V. 64. — № 5. — P. 642-645.
2. Duchowicz R., Ferrer M.L., Ulises Acuiiat A. Kinetic spectroscopy of erythrosine phosphorescence and delayed fluorescence in aqueous solution at room temperature. / / Photochemistry and Photobiology. — 1998. — V. 68. — № 4. — P. 494-501.
3. Bryukhanov VV, Ketsle GA, Laurinas V.Ch., Levshin LV, Muldakhmetov ZM Singlet-triplet annihilation of singlet oxygen and triplet xanthene dye molecules in liquid solution / / Zhurnal prikladnoi spectroskopii. — 1987. — V. 46. — № 4. — P. 588-593.
4. Melnikov AG, Saletsky AM, Kochubey VI, Pravdin AB, Kurchatov, IS, Mel'nikov GV Triplet-triplet energy transfer between fluorescent probes bound to the albumin / Optics and Spectroscopy. — 2010. — T. 109. — № 2. — S. 216-221.
5. Moiseeva E.V. Original approaches to test anti-breast cancer drugs in a novel set of mouse models. Proefschrift, 2005.
6. Letuta SN Maryahina VS Rakhmatullin RR, Zabirov RA Process for obtaining viable cells of the breast. The decision on granting a patent number 2009 116 530 from 10.08.2010.
7. Rohatgi-Mukherjee K.K., Mukhopadhyay A.K. Photophysical processes in halofluorescein dyes / / Indian J. of Pure and Applied Phys. — 1976. — V. 14. — P. 481.
8. Dobretsov GE Fluorescent probes to study cell membranes and lipoproteins. Moscow: Nauka, 1989. 277.
9. Terenin AN Photonics of dye molecules. Moscow: Nauka, 1967.
10. Kenner R.D., Khan A.U. Molecular oxygen enhansed fluorescence of organic molecules in polymer matrices: a singlet oxygen feedback mechanism / / J. Chem. Phys. — 1976. — V. 64. — P. 1877.
11. Kucherenko MG, Ketsle GA, Miller MP, Letuta SN 0 // Известия АН СССР." Hd="Selective laser gain fluctuation rates of the reactions A + B 0 / / Izv. " closure_uid_c36gu4="137"Selective laser gain fluctuation rates of the reactions A + B> 0 / / Izv. Ser. nat. — 1993. — T. 57 . — p.175.
12. Kucherenko MG, Ketsle GA, Miller MP, Letuta SN Change in the kinetics of the annihilation of the luminescence of dyes in polymers by the laser pulse, "Opt. and spectrum. — 1995. — T. 78. — S. 649.
13. Emmanuel, NM, Kavetsky RE, Tarusov BN Sidorik EP Biophysics of cancer. Kiev: Naukova Dumka, 1976. — 287.
14. Gorenkov RV, Karpov VN, Rogatkin DA, Shumsky, VI Chronic hypoxia as a factor in increased fluorescence of endogenous porphyrins in alive biological tissues / / Biophysics. — 2007. — T. 52. — S. 711.
About this article
Authors: Maryahina V.S., Rahmatullin R.R., Letuta S.N., Pashkevich S.N.
Year: 2011
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Editor-in-chief |
Sergey Aleksandrovich MIROSHNIKOV |
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