2015, № 12 (187)

Zelentsov K.S., Ioileva E.E., Zelentsov S.N. USE OF POLARIZING MIXTURE IN TREATMENT OF CLOSED EYE INJURYClosed eye injury ranks second in frequency among all eye contusions. 40.7–46.5 % of patients have ophthalmoscopically visible changes ofretina. 0.5–23.7 % of patients suffer from traumatic optic neuropathy. Nowadays a wide variety of conservative methods of treatment of retina and ophthalmic nerve contusion changes is used. Nevertheless most of them are not efficient enough due to the fact that they don't produce an ethiopathogenetic effect. To study a neuroprotective effect of polarizing mixture (glucose-insulin-potassium) on retina and ophthalmic nerve neuron metabolism in case of eye injury, for 1–3 days after trauma there was examined functional status of retina and ophthalmic nerve of 20 patients with eyeball injury and transparent optical media. There were used objective methods: registration of general electroretinogram (ERG) and visually evoked potentials (VEP) by a diagnostic suite "Electroretinograph" (produced by MBN, Russia). Eye stimulation was held monocularly, with diffusive flashes of white light, flash energy was 0,3 J, frequence was 1 Hz. The acquired data was statistically analyzed. The research has found that according to the electroretinogram data one hour after injection of polarizing mixture wave "а" is registered to increase by 135 % and wave "b" — by 164 %. The amplitude of the wave P-100 VEP increases by 161 %. Thus, on the basis of the received data, we believe that using of polarizing mixture produces a neuroprotective effect on retina and ophthalmic nerve in case of closed eye injury.Key words: eye contusion, electroretinogram, visual evoked potentials, polarizing mixture.

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About this article

Authors: Ioyleva E.E., Zelentsov K.S., Zelentsov S.N.

Year: 2015

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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