June 2016, № 6 (194)

Avdeeva Y.A., Medvedeva O.A., Korolev V.A., Kalutskii P.A. INFLUENCE OF PROBIOTICS BACTISTATIN AND NORMOBACT ON THE COMPOSITION OF THE MICROBIOCENOSIS OF THE LARGE INTESTINE IN EXPERIMENTAL DYSBIOSISChange in the qualitative and quantitative structure of microbiocenosis of the colon of — dysbiosis is a background condition for the development of a large spectrum of diseases, and also — factor in the weakening of the immune system. Studied Influence of drugs with pronounced probiotic effect of bactistatin and normobact on the composition of the microflora of the large intestine in experimental dysbiosis of gentamicin. Correction of dysbiosis due to gentamicin with probiotics bactistatin and normobact led to change in the quantitative and qualitative composition of representatives of the mucosal microbiota of the colon. Use of bactistatin and normobact led to normalization of content 12 of 13 and 9 of 13 microorganisms, respectively, defined in the composition of the mucosal microflora of the colon. A more pronounced effect of the correction of the quantitative and qualitative composition of the intestinal microflora observed in the use of the drug bactistatin. In our opinion, the differences in the normalization of the microbiota of the large intestine, associated with the species composition of microorganisms used in probiotics. This allows to recommend in clinical practice the use of these drugs for the selective correction of dysbiosis after the study of qualitative and quantitative structure of microbiocenosis of the large intestine.Key words: mucosal microflora of the large intestine, dysbiosis, bactistatin, normobact.

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About this article

Authors: Avdeeva Yu.A., Kalutskiy A.P., Medvedeva O.A., Korolev V.A.

Year: 2016

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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