2015, № 12 (187)

Shaimova T.A., Panova I.E., Ermak E.M. OCT-PARAMETERS OF CHORIORETINAL COMPLEX IN PATIENTS WITH COMBINED PATHOLOGY — AGE-RELATED MACULAR DEGENERATION AND PRIMARY OPEN ANGLE GLAUCOMAAge-related macular degeneration (AMD), and primary open angle glaucoma (POAG) — the main reasons for the decrease of visual function and quality of life in older age and advanced age patients. The purpose of this study is to identify the OCT-parameters features of chorioretinal complex in patients with combined pathology — the dry form of AMD and POAG. There were 98 patients (192 eyes), we identified three study groups (SG): SG1 — AMD with POAG — 63 eyes; SG2 — AMD without neuroopticopathy — 56 eyes, SG3 — POAG without AMD — 40 eyes; the average age — 75.7 ± 6.5 years. Manually measure of the neuro-sensory retina (NSR) thickness, the ganglion cells complex (GCC) thickness and the choroid thickness by optical coherence tomography were performed in two areas: 4 mm lateral (area I) and 4 mm medial (area II) to the optic nerve head. Index of GCC thickness (GCCT) was calculated equal to the ratio: GCC thickness/ NSR thickness. It was found that in patients with combined pathology — AMD and POAG (SG1) thickness of the NSR, thickness of the GCC, index of GCCT and choroid thickness significantly reduced in the area I and II in comparison with the control group. In the patients of SG1 NSR thickness, GCC thickness, index of GCCT was significantly lower in area I and II; choroidal thickness was lower in the area I and significantly lower in area II in comparison with patients of SG2. The research results of OCT-parameters of chorioretinal complex in patients with combined pathology (AMD and POAG) determined the severity of progressive course of AMD in patients with POAG predominance of atrophic form.Key words: age-related macular degeneration, primary open-angle glaucoma, optical coherence tomography, retinal ganglion cells, choroid.

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About this article

Authors: Shaimova T.A., Panova I.E., Ermak E.M.

Year: 2015

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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