October 2015, № 10 (185)

Zhirnikova Е.Yu., Kunavina E.A. IR-SPECTROSCOPIC STUDY OF THE DRUG "DICLOFENAC" DIFFERENT MANUFACTURERSThis article provides an IR-spectroscopic characterization of popular on the pharmaceutical market drug "Diclofenac" in pill form three different manufacturers — "Ozon", "Hemofarm", Pharmaceutical company "Obolenskoe". The comparative analysis of infrared spectra. In all the samples based on the data of the IR spectra identified the main active ingredient of the medicinal product sodium salt of 2-[(2,6-dichlorophenyl)amino]-phenylacetic acid. In the experimental part presents the methodology of analysis of investigational product, lay down the conditions for recording infrared spectra. It is shown that the method of IR spectroscopy is applicable for the evaluation of authenticity of pharmaceutical drug "Diclofenac" and with a sufficient degree of accuracy can confirm the presence or absence of the medicinal product main active ingredient stated on the packaging.Key words: drug "Diclofenac", identification, IR spectroscopy, sodium salt of 2-[(2,6-dichlorophenyl)amino]-phenylacetic acid.

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About this article

Authors: Zhirnikova E.Yu., Kunavina E.A.

Year: 2015

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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