March 2015, № 3 (178)

Karmanova D.C., Chesnokova L.A., Krasikov S.I. THE IMPACT OF NON-TOXIC DOSES OF THE HERBICIDE 2,4-DA ON THE DYNAMICS OF BODY WEIGHT OF ANIMALS IN THE EXPERIMENTThe article is devoted to assessing the possible role of the herbicide 2,4-DA (2,4-dichlorophenoxy acid dimethylammonium salt) in the development of overweight in long-term intake of low doses of the substance in the organism of laboratory animals with drinking water. This herbicide is of particular interest, since on the one hand it is widely used in agriculture and its inherent unique combination of such qualities as chemical stability and high lipophilicity contribute to its accumulation in the objects of wildlife and the delay in the body. The results of these studies showed that the uptake of the herbicide 2,4-DA led to a more rapid increase in body weight than the control animals. At the same time, in the experimental group rats showed greater accumulation of adipose tissue, as measured by the criterion weight indicate epididymal fat. Overall, the results showed that the intake of pesticide in doses that are an order of magnitude below the maximum allowable, indicate that when assessing the effects of pollutants of anthropogenic origin, should be paid not only on the ecological validity of these pollutants, but also on the fact of their presence, even at doses that do not have toxic effects.Key words: herbicide, 2,4- dichlorophenoxyacetic acid dimethylammonium salt, obesity

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About this article

Author: Krasikov S.I.

Year: 2015

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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