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2014, № 12 (173)



Belyiy Yu.А., Novikov S.V., Kolesnik А.I., Yudina Yu.А. INTRAVITREAL IMPLANT FOR DRUG DELIVERY TO THE POSTERIOR SEGMENT STRUCTURES OF THE EYEDevelopment and experimental substantiation of the method of drug delivery to the structures of the posterior segment using biodegradable intravitreal implant are considered. The peculiarity of the implant is the possibility of alternation of saturated and unsaturated medicinal substance layers. During studying of process of degradation of unsaturated implant was found that the degradation of the polymer backbone of the implant was by hydrolysis. The proposed implant provides periodic selection of the active substance that prevents the excess of the therapeutic drug concentrations in the environment due to the design of the implant.Key words: delivery of medicines, the intravitreal implant.

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About this article

Authors: Belyy Yu.A., Yudina Yu.A., Novikov S.V.

Year: 2014


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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