Vestnik On-line
Orenburg State University december 22, 2024   RU/EN
Headings of Vestnik
Pedagogics
Psychology
Other

Search
Vak
Антиплагиат
Orcid
Viniti
ЭБС Лань
Rsl
Лицензия Creative Commons

2012, № 12 (148)



Solodkova E.G., Melikhova I.A. CORNEAL COLLAGEN CROSSLINKING SAFETY EVALUATION IN TREATMENT OF PROGRESSIVE KERATOCONUS BASING ON REMOTE POSTOPERATIVE RESULTSSafety and efficiency of two corneal collagen crosslinking (CXL) techniques was brought to comparative analysis. CXL was performed in 25 patients with progressive keratoconus: 9 patients (9 eyes) underwent a conventional CXL; 16 patients (16 eyes) had a modified CXL which novelty consisted of a depth-metered deepithelialization performed by excimer laser with on-line pachymetry Schwind Amaris (Germany). UV-A exposure was made by means of "UV-X" device (version 1000) (IROC Inc., Switzerland). All patients were prescribed to wear silicon-hydrogel soft contact lenses until a complete epithelial recovery. Improvement of NCVA, BCVA, topographic parameters, pachymetric values along with integrity of endothelial cell density was registered in all the cases which allows concluding that both CXL methods are safe and effective. Key words: corneal collagen crosslinking, keratoconus.

Download
References:

1. Bahar I., Kaiserman I., Srinivasan S. et al. Comparison of three different techniques of corneal transplantation for keratoconus // Int. Ophthalmol. — 2008. — Vol. 28(3) — P.141-146.

2. Bland J.M., Butland B.K., Peacock J.L., Poloniecki J., Reid F., Sedgwick P. Statistics Guide for Research Grant Applicants // St George's Hospital Medical School, London. — 2009. — P.41.

3. Colin J., Cochner B., Savary G. et al. Correcting keratoconus with intracorneal rings // J. Cataract. Refract. Surg. — 2000. — Vol. 26. — P.1117-1122.

4. Ferrara de A., Cunha P. Tecnica cirurgica para correcao de myopia. Аnel corneano intra-estromal // Rev. Bras. Oftalmol. — 1995. — Vol. 54. — P.577-588.

5. Holladay J.T., Prager T.C. Mean visual acuity // Am. J. of Ophthal. — 1991. — Vol. 3. — Р.372-373.

6. Kim W.J., Rabinowitz Y.S., Meisler D.M., Wilson S.E. Keratocyte apoptosis associated with keratokonus // Exp Eye Res. — 1999. — Vol. 69. — P.475-481.

7. Mazzotta C., Balestrazzi A., Biaocchi S. et al. Stromal haze after combined riboflavin-UVA corneal collagen cross-linking in keratokonus: in vivo confocal microscopic evaluation // Clin. Experiment Ophthalmol. — 2007. — Vol. 35(6). — P.580-582.

8. Mishima H., Abe K., Otori T. Regulatory mechanismus of procollagenase synthes by keratocytes // In: Lass JH ed. Advances in corneal research. New York: Plenum Press. — 1996.

9. Price F.W., Price M.O., Adult keratoplasty: has the prognosis improved in the last 25 years? // Int. Ophthalmol. — 2008. — Vol. 28(3). — P.141-146.

10. Raiskup F., Hoyer A., Spoerl E. Permanent corneal haze after riboflavin-UVA-induced cross-linking in keratokonus // J. Refract. Surg. — 2009. — Vol. 25(9). — P.824-828.

11. Roe R.H., Lass J.H., Brown G.C., Brown M.M. The value-based medicine comparative effectiveness and cost — effectiveness of penetrating keratoplasty for keratoconus // Cornea — 2008. — Vol. 27(9). — P.1001-1007.

12. Spoerl E., Schreiber J., Hellmund K., Seiler T., Knuschke P. Crosslinking Effects in the cornea of Rabbits // Ophthalmologe. — 2000. — Vol. 97. — P.203-206.

13. Spoerl E., Wollensak G., Dittert D., Seiler T. Thermomechanical Behavior of Collagen-Crosslinked Porcine Cornea // Ophthalmologica. — 2004. — Vol. 218. — P.136-140.

14. Spoerl E., Wollensak G., Seiler T. Increased Resistance of Crosslinkinked Cornea against Enzymatic Digestion // Current Eye Research — 2004. — Vol. 29(1). — P.35-40.

15. Wollensak G., Spoerl E., Seiler T. Riboflavin/Ultraviolet-A Induced Collagen– Crosslinking for the Treatment of Keratokonus // Am. J. Oftalmol. — 2003. — Vol. 135. — P.620-627.

16. Wollensak G., Wilsch M., Spoerl E., Seiler T. Collagen Fiber Diameter in the Rabbit Cornea after Collagen — Crosslinking by Riboflavin/UVA // J. Cornea. -2004. — Vol. 23(5). — P.503-507.


About this article

Authors: Melihova I.A., Solodkova E.G.

Year: 2012


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

Crossref
Cyberleninka
Doi
Europeanlibrary
Googleacademy
scienceindex
worldcat
© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru
1999–2024 © CIT OSU