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2012, № 6 (142)



Kopylov V.A., Nikitenko I.E., Mihanov V.A., Polyakova V.S., Abzeneleva R.A. USING THE "VINFAR" ON THE BASIS OF FIBROBLAST GROWTH FACTOR FOR DERMAL AUTOPLASTYOpen fractures are often accompanied by defects of the soft tissues. One way to treat it is autodermoplasty. The frequency of graft rejection after autodermoplasty remains high. We have new drug named "Vinfar" on the basis of human fibroblast growth factor. As a result of experimental work provided evidence that use of this drug in autodermoplasty significantly accelerates the adhesion of the graft, decreasing incidence of graft rejection and improving reparative processes in the wound area.Key words: open fracture, dermal autoplasty, fibroblast growth factor, skin defect.

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References:

1. Shapkin, U.G. Way to improve the efficiency of plastic wound closure after frostbite // Annals of surgery. — 2010. — №5. — P. 72–74.

2. Bottcher R.T., Niehrs C. Fibroblast growth factor signaling during early vertebrate development // Endocr. Rev. — 26 (1). — P. 63–77.

3. Bendfeldt K., Radojevic V., Kapfhammer J. Basic fibroblast growth factor modulates density of blood vessels and preserves tight junctions in organotypic cortical cultures of mice: a new in vitro model of the blood-brain barrier // J Neurosci. — 2007. — Mar 21;27(12). — P. 3260–3267.

4. Akita S., Akino K., Imaizumi T. Basic fibroblast growth factor accelerates and improves second-degree burn wound healing // Wound Repair Regen. — 2008. — Sep-Oct;16(5). — P. 635–641.

5. Yao C., Yao P., Wu H., Zha Z. Acceleration of wound healing in traumatic ulcers by absorbable collagen sponge containing recombinant basic fibroblast growth factor // Biomed Mater. — 2006. — Mar;1(1). — P. 33–37.

6. Patent № 2427644 С1 RU МПК С12N А61К. The strain of Bacillus subtilis — producer of fibroblast growth factor. V.I. Niki-tenko. — Publ. 27.08.11. Vol. № 24.


About this article

Authors: Kopylov V.A., Nikitenko I.E., Mihanov V.A., Polyakova V.S., Abzeneleva R.A.

Year: 2012


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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