2011, № 12

Burakaeva A.D, Karpova G.V. NEW ANTIFUNGAL ANTIBIOTIC PRODUCTION IN HYPOMYCES ROSELLUS AND PHENOTYPICALLY STRAINSAntibiotics by Hypomyces rosellus and phenotypically strains are isolated and their chemical composition was studied. Using thin-layer chromatographe, mass spectrometry, IR and UF spectroscopy, chromatomass spectrometry, ЯМР 1Н 1-[[2-(2,4-Dichlorophenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole and 5 individual dioxolans was indentified. Antibiotics inhibited the growth of pathogenic fungi.Key words: micophilous fungus Hypomyces rosellus, antibiotic, dichlorophenyl, dioxolan, triazole.

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References:

1. Toropova E.G., Maximov V.N., Beresneva G.G., Egorov N.S., Burakaeva A.D. Optimizathion of composithion of medium for biosynthesis of antibiotic, proteases and pigment by Hypomyces rosellus with mathematical design of experiment //Antibiotics and medical biothechnology.- 1986. — № 6.- С.408 -411.

2. Toropova E.G., Mardamshina A.D. (Burakaeva), Piskunkova N.F. Choosing of seed media, mycelium age and quantity providing simultaneous biosynhesis of antibiotic and pigment by Hypomyces rosellus. //Antibiotics and chemistry terapia.-1988/- №2.-С.96-99.

3. Egorov H.S. Stadies of antibiotics. -М.-2005.-Р.43,155-160, 340-523.

About this article

Authors: Burakaeva A.D., Karpova G.V.

Year: 2011

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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