Valeyeva L.A., Kulagina I.G., Yafayeva E.G.
THE EFFECT OF DIAZEPAM ON MOTION ACTIVITY OF RATS DEPENDING ON THE CIRCADIAN TIME AND DENSITY OF CEREBRAL GABA RECEPTORS ^{[№ 6 ' 2014]}
The effect of diazepam on motion activity in rats after morning and evening introduction has been studied. It has been found that maximal suppressing effect of the medecation on the motion coefficient in a test "open area" is observed after evening introduction at the highest density of cerebral GABA receptors. After morning injection the suppressing effect is observed twice, i.e. immediately after the injection and during evening hours against the background of receptor increase.