Vestnik On-line
Orenburg State University november 24, 2024   RU/EN
Headings of Vestnik
Pedagogics
Psychology
Other

Search
Vak
Антиплагиат
Orcid
Viniti
ЭБС Лань
Rsl
Лицензия Creative Commons

2015, № 12 (187)



Shevchenko M.V., Shugurova N.E., Siradzinova D.R. BIOMETRIC EVALUATION OF THE CORNEA IN PRIMARY OPEN-ANGLE GLAUCOMA IN THE DYNAMICSIn recent years, more attention takes corneal biomechanical parameters and their relationship with the development of glaucoma. Central corneal thickness (CCT) of all parameters currently the most available for use in clinical practice. The aim of the work was to assess the state of the central corneal thickness in patients with primary open angle glaucoma (POAG) in the course of 7 years depending on the stage of the process and its initial parameters. In 106 patients (147 eyes), corneal thickness was evaluated in dynamics within 7 years. The control group consisted of 235 healthy individuals (470 eyes). In the study group the average value of the central corneal thickness was 537.49 μ ± 33.83 μ, which was significantly less than in the control 555.48 μ ± 39.85 μ (t = 9.1; p < 0.01). At 82.3 % of patients with POAG central corneal thickness decreased by an average of 10.51 μ ± 11.81 μ, compared with the control group (35 % decrease of 0.29 μ ± 10.61 μ). During seven years there was a tendency to a decrease of the central corneal thickness both average and at different initial corneal thickness. This is significantly different from the control group. In addition, the reduction of the central corneal thickness in patients with primary open angle glaucoma increases with increasing time of observation (9.99 μ ± 12.47 μ at the observation 1–3 years, 12.11 μ ± 13.22 μ at the observation 4–7 years). The individual values of dynamic control of the central corneal thickness in patients with POAG for 7 years showed a statistically significant decrease in 82.6 % of cases. Reducing the thickness of the cornea is independent of its initial value and the stage of glaucoma.Key words: open-angle glaucoma, central corneal thickness, pachymetry.

Download
References:

1. Avetisov S.E.,Egorov E.A., Moshetova L.K., Neroev V.V., Tahchidi X.P. Ophthalmologia. Natsionalnoe rukovodstvo [Ophthalmology. National guidlance.] Moscow, GEOTAR-Media, 2011,-P. 994 (In Russ.)

2. Alekseev V.V. Ocenka vliyaniya parametrov rogovoj obolochki na rezul'taty tonometrii v zdorovoj populyacii. [Evaluation of influence of corneal parameters on tonometric results in normal subjects.] Clinical ophthalmology.-2008.-Vol.9.-No.4.-P.128-130 (In Russ).

3. Alexeev V.N., Litvin I.B. Vliyanie tolschinyi rogovitsyi na uroven vnutriglaznogo davleniya i prognoz pri pervichnoy otkryitougolnoy glaukome [Influence of corneal thickness on IOP level and prognosis in POAG.] Clinical ophthalmology.-2008.-Vol.1.-No.4.-P.130-133 (In Russ.)

4. Volkov V.V. Dopolnitelnoe obosnovanie predlagaemoy dlya obsuzhdeniya klassifikatsii otkryitougolnoy glaukomyi na osnove predstavleniy o patogenze ee progressirovaniya [Additional rationale for the open-angle glaucoma classification to be discussed, by using the concepts of the pathogenesis of its progression.] Annals of ophthalmology.-2007.-No. 4.-P.40-45

5. Egorov E.A., Astakhov Yu.S., Shchuko A.G. Natsionalnoe rukovodstvo po glaukome dlya praktikuyushchikh vrachei, 2-e izd [National glaucoma guidlance for medical practitioners. 2nd ed.]. Moscow, GEOTAR-Media, 2011, P. 280 (In Russ.)

6. Egorov E.A., Vasina M.V. Vliyanie tolshchiny rogovicy na uroven' vnutriglaznogo davleniya sredi razlichnyh grupp pacientov. [Influence of corneal thickness on IOP level in different groups of patients.] Clinical ophthalmoiogy. 2006. No.1. P.16-19 (In Russ)

7. Kachanov A.B., Golovatenko S.L., Nikulin S.A. Vliyanie tolshchiny rogovicy na pokazateli vnutriglaznogo davleniya. [Effect of the corneal thickness on intraocular pressure.] Abstracts of the VIIIth Congress of Russian Ophthalmologists, M., 2005. P/179-180 (InRuss)

8. Moshetova L.K., Alekseev I.B., Zubkova A.A. Izmeneniya biomehanicheskih svoystv rogovitsyi u bolnyih s razlichnyimi stadiyami pervichnoy otkryitougolnoy glaukomyi. [Changes in the biomechanical properties of the cornea in patients with different stages of primary open angle glaucoma.] Oftal'mologicheskie vedomosti -2011. -Vol.-4, No.-2. 26-29P. (In Russ)

9. Neroev V.V., Kiseleva O.A., YAkubova L.V., Eremina M.V. Sravnitel'nyj analiz central'noj tolshchiny rogovicy i ee vliyanie na pokazateli tonometrii v norme i u bol'nyh pervichnoj otkrytougol'noj glaukomoj. [Comparative analysis of central corneal thickness and its effect on the tonometry in normal and in patients with primary open-angle glaucoma.] collection of works "8th All-Russian School ophthalmologist". Moscow.- 2009.- P.176-179.(In Russ)

10. Collin G., Nurphy Ph.D., Anderson J. et al. Localization of extracellular proteins of the human traberular meshwork by indirect immunofluorescence // Amer.J.Ophthalmol.-1987.-Vol. 104.- No 1.-P. 33-43.

11. Congdon N.G., Broman A.T., Bandeen-Roche K., Grover D., Quigley H.A. Central corneal thickness and corneal hysteresis associated with glaucoma damage. Am. J. Ophthalmol. V.141, I.5, 2006, P.868–875.

12. Gordon M.O., Beiser J.A., Brondt J.D. et al. The ocular hypertension treatment study: baseline factors that predict the onset of primary open-angle glaucoma. // Arch. Ophthalmol.-2002.-Vol. 120.-P.714-720.

13. Jonas J.B., Stroux A., Velten I., Juenemann A., Martus P., Budde W.M. Central corneal thickness correlated with glaucoma damage and rate of progression.// Invest Ophthalmol Vis Sci. 2005 Apr;46(4):1269-74.

14. Hernandez M.R., Pena J.D., Selvidge J.A. Hydrostatic pressure stimulates synthesis of elastin in cultured optic nerve head astrocytes // Glia.- 2000.- Vol.32.-No.2.-P.122-136.

15. Sigal I.A., Flanogan J.G., Ethier C.R. Factors influencing optic nerve head biomechanics// Invest. Ophthalmol. Vis.Sci.-2005.-Vol.46.- No.11.-P.4189-4199.


About this article

Authors: Sirazitdinova D.R., Shevchenko M.V., Shugurova N.E.

Year: 2015


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

Crossref
Cyberleninka
Doi
Europeanlibrary
Googleacademy
scienceindex
worldcat
© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru
1999–2024 © CIT OSU