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2014, № 6 (167)



Korneev G.I., Lizurchik L.V., Sipaylova O.Yu, Lebedev S.V., Sheyda E.V. MORPHOFUNCTIONAL CHANGES OF THE FETOPLACENTAL COMPLEX RATS ON THE BACKGROUND OF TOBACCO INTOXICATIONThe work presents the results of studying the influence of the tobacco intoxication on the feto-placental complex of white rats using experimental model of "passive Smoking". Revealed pathological signs of placental insufficiency (reduction of the weight and thickness of placentae; reducing the number of fruit capillaries and maternal sinuses while reducing their diameters; cir-culatory disorders in the form of a sharp hyperemia, edema, hemorrhage in the labyrinth layer placenta; foci of ischemia and thrombosis maternal gaps with the development of a major ischemic heart attacks; the formation of large pockets of destruction of trophoblast cells with the formation of various sizes cavities and other), which contributed to the delay in fetal develop-ment and the emergence of cases of fetal death.Key words: Smoking, fetoplacental complex, placental insufficiency, rats, prenatal development.

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References:

1. Alijanova I.A., Notova S.V., Kiyaeva E.V., Miroshnikov S.A., NesterovD.V. Assessment metabolic parameters and hormonal status in stress conditions // Medline.ru. — 2012. T. 13. — №3. — S. 748-753.

2. Avtandilov — Medical morphometry. — M: Medicine, 1990. — 384 S.

3. Gulyaeva, NI is the fetoplacental complex in white rats after injection of staphylococcal toxin / N. Gulyaev, S. Melekhin, EL Kondratska, G.T. Valiulina, MR Mukhamedzyanova // Successes of modern natural science — 2006. — №12. — 51 C..

4. Jubilo, A.V. The effect of Smoking on the implementation of the reproductive function of women / the A.V. Jubilo // Vestnik of Samara state University — natural Science series. — 2010. — №6 (80). — S. 187-190.

5. G. A. Merkulov Course histotechniques. L.: Agropromizdat, 1980. — 339 S.

6. Smolnikova, N.M. Methodical instructions for study of reproductive toxic property of phar-macological substances. Guide preclinical experimental-mu study of new pharmacological sub-stances [Text] / N.M.Smolnikova, B. I. Lyubimov, A.D. Durnev, A.M. Skosyreva, E.M Chirk-ova, T.A. Guskova, I.V. Golovano-VA, R.D. Subaev, O.L.Verstakova. — M, 2005. — S. 87-100.

7. Solomin A.S. Dissertation on competition of a scientific degree of candidate of biological Sci-ences. 14.03.06 — Formalogy clinical pharmacology, Moscow, 2006, s.

8. Zinserling V.A. Perinatal infection.(Questions of pathogenesis, morphological diagnostics and clinical-morphological comparisons).A practical guide / V.A.Tsinzerling, Ms. V. Melnikov. — SPb.: AlbiSPb, 2002. — 352 S.

9. ShabalovaA. N. Neonatology. — M: "Medpress-inform". — 2006. — Vol.1. — S. 109-114.

10.Husgafvel-Pursiainen, K. Genotoxicity of environmental tobacco smoke: a review [Text] / K. Husgafvel-Pursiainen // Mutat Res. — 2004. — Vol. 567, №2-3. — Р. 427-445.

11.Klonoff-Cohen H.S. et al.// Jama. — 1995. — Vol. 273. — P. 795.

12. Lips K.S. Nicotinic acetylcholine receptors in rat and human placenta [Text]/ K.S. Lips, D. Bruggmann, U. Pfiel, et al. // Placenta. — 2005. — Vol. 26, №10. — Р. 735-746.

13.Nelson, E. Maternal passive smoking during pregnancy and fetal developmental toxicity. Part 1: gross morphological effects [Text] / E. Nelson, K. Jodscheit, Y. Guo // Human and Experi-mental Toxicology. — 1999. — Vol. 18. — P. 252-256.

14. Nelson, E. Maternal passive smoking during pregnancy and fetal devlopmental toxicity. Part 2: histologicalchenges [Text] / E. Nelson, C. Goubet-Wiemers, Y. Guo // Human and Ex-perimental Toxicology. — 1999. — Vol. 18, №14. — P. 257-264.


About this article

Authors: Sipaylova O.Yu., Korneev G.I., Lizurchik L.V., Lebedev S.V., Sheyda E.V.

Year: 2014


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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