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2010, № 5



Selezneva E.S., Belousova Z.P., Moiseeva L.M. GENOTOXICITY OF SYNTHETIC PHENOLIC DERIVATIVES OF BENZIMIDAZOLE We studied genotoxicity for Allium sulfur benzimidazolilmethylphenol and 2-methyl benzimidazolilmethylphenols. It is shown that it depends on the position of the OH group in the benzene ring, in particular, 4-substituted phenols are more genotoxic than 2-substituted ones. Possible mechanisms of action of these compounds are discussed. Key words: benzimidazole, phenols, genotoxicity, mitotic index, chromosomal aberrations, Allium sulfur

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About this article

Authors: Selezneva E.S., Belousova Z.P., Moiseeva L.M.

Year: 2010


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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