Berdnikova E.V., Solyanikova O.V., Ekgardt V.F., Dmitrienko V.N.
PREDICTION COMPENSATION OF INTRAOCULAR PRESSURE IN PATIENTS WITH PRIMARY OPEN-ANGLE GLAUCOMA DEPENDING ON THE STAGE OF THE DISEASE ^{[№ 12 ' 2015]}
Glaucoma occupies the third place in the world in the structure of causes of blindness after cataract and diabetes mellitus. Primary open-angle glaucoma (POAG) is considered as a multifactorial disease, the most important risk factor for the development and progression of which is elevated intraocular pressure (IOP). Prediction of compensation IOP in patients with POAG is important. Factors of IOP stability were determined and method for the prediction of IOP compensation depending on the stage of the disease in patients with POAG was developed on the basis of the dynamic observation for one year 150 patients with POAG using discriminant analysis. Observation included a comprehensive assessment of central and peripheral vision, eye and orbital hemodynamics, parameters of general hemodynamic, state of the system "lipid peroxidation — antioxidant protection", lipid profile and the affective-cognitive status of patient. The method presented in the article allows predicting a highly specific forecast (more then 90 %) about maintaining of intraocular pressure target level during 12 months of follow-up.

Soljannikova O.V., Berdnikova E.V., Jekgardt V.F., Tur E.V.
FORECASTING OF DYNAMICS OF VISUAL FUNCTIONS IN PATIENTS WITH PRIMARY OPEN-ANGLE GLAUCOMA DEPENDING ON THE STAGE OF THE DISEASE ^{[№ 12 ' 2015]}
Primary open-angle glaucoma (POAG) is the most common eye disease with a progressive course even when the intraocular pressure, the main factor of progression of this disease, is compensated a large percentage of patients with glaucoma have deterioration in visual function. Forecast of changing of visual functions in POAG that are the most important component of patient's quality of life is a critical task. Method for the prediction of visual functions changes depending on the stage of the disease in patients with POAG who achieved "target" intraocular pressure was developed on the basis of the dynamic observation for one year 150 patients with POAG using discriminant analysis. Observation included a comprehensive assessment of central and peripheral vision, eye and orbital hemodynamics, parameters of general hemodynamic, state of the system "lipid peroxidation — antioxidant protection", lipid profile and the affective-cognitive status of patient. The method presented in the article allows predicting a deterioration or stable state of the eye functions in POAG-patients with high (over 90 %) specificity.