Shevchenko M.V., Shugurova N.E., Siradzinova D.R.
BIOMETRIC EVALUATION OF THE CORNEA IN PRIMARY OPEN-ANGLE GLAUCOMA IN THE DYNAMICS ^{[№ 12 ' 2015]}
In recent years, more attention takes corneal biomechanical parameters and their relationship with the development of glaucoma. Central corneal thickness (CCT) of all parameters currently the most available for use in clinical practice. The aim of the work was to assess the state of the central corneal thickness in patients with primary open angle glaucoma (POAG) in the course of 7 years depending on the stage of the process and its initial parameters. In 106 patients (147 eyes), corneal thickness was evaluated in dynamics within 7 years. The control group consisted of 235 healthy individuals (470 eyes). In the study group the average value of the central corneal thickness was 537.49 μ ± 33.83 μ, which was significantly less than in the control 555.48 μ ± 39.85 μ (t = 9.1; p < 0.01). At 82.3 % of patients with POAG central corneal thickness decreased by an average of 10.51 μ ± 11.81 μ, compared with the control group (35 % decrease of 0.29 μ ± 10.61 μ). During seven years there was a tendency to a decrease of the central corneal thickness both average and at different initial corneal thickness. This is significantly different from the control group. In addition, the reduction of the central corneal thickness in patients with primary open angle glaucoma increases with increasing time of observation (9.99 μ ± 12.47 μ at the observation 1–3 years, 12.11 μ ± 13.22 μ at the observation 4–7 years). The individual values of dynamic control of the central corneal thickness in patients with POAG for 7 years showed a statistically significant decrease in 82.6 % of cases. Reducing the thickness of the cornea is independent of its initial value and the stage of glaucoma.