|
|
|
Камилов Ф.Х.
Bikmetova E.R., Menshikova I.A., Ramazanova L.M., Ivanova G.V., Kamilov F.Kh.
EFFECTIVENESS OF ACTIVITY OF ANTIOXIDANT VITAMINOUS PREPARATION ON METABOLISM OF BONE TISSUE AT CHRONIC INTOXICATION BY THE DICHLOROETHANE DURING THE EXPERIMENT
Chronic (during two months) dayly intoxication by the dichloroethane in the cumulative doze of 0,1 LD50 of mature white rats causes strengthening the processes of free-radical oxidation, reduction in the activity of the ferments of antioxidant protection and increase in the content of free hydroxiprolin in homogenates of the epiphyses of tubular bones. In the plasma of the blood of experimental animals the level S-bodypeptids of a collagen of the type I repeatedly increases with the constant activity of bone alkaline phosphatase. The treatment of animals by vitamin preparation "Triovit" during three weeks at the dose of 50 mg/kg in a 24 hour period against the background to intoxication by dichloroethane renders positive therapeutic effect on the exchange of the bone, reducing the intensity of chemiluminescence, the accumulation of the primary and secondary products of lipoperoxidation, strengthening the activity of fermentation antioxidants, suppressing resorptive processes.
Key words: dichloroethane, intoxication, bone tissue, metabolism, antioxidants.
Kamilov F.H. , Mamcev A.N., Abdullina G.M., Lobyreva О.V.
ESTIMATION OF EFFICIENCY IODINEPOLYSACCHARIDE COMPLEX IN CORRECTION OF OXIDIZING METABOLISM AT EXPERIMENTAL THYROPRIVIA
In the article the results of research of activity of enzymes of power exchange of liver of rats are presented with a merkasolilovym thyroprivia and at his correction a iodinepolysaccharide complex "iodine-pectin". It is set that experimental thyroprivia, accompanied by the decline of activity of mitokhondrialnykh enzymes — malat- and glutamatdegidrogenas with the simultaneous increase of activity of suksinatdegidrogenases. The results of the conducted research testify to tireotropny activity of organomineral complex "iodine-pectin".
Key words: enzymes, polysaccharide complex, oxidizing metabolism.
Ramazanova L.M., Menshikova I.A., Kamilov F.H.
BONE MINERAL DENSITY DISTURBANCE IN MEN WORKING IN CHEMICAL MANUFACTUTE
Ultrasound densitometry of certain parts of skeleton (proximal phalanx of III finger, shin bone, spoke bone) of childbearing age men, working at chemical enterprises and having permanent contact with organic chlorine compounds (dichloroethane, 3-chlorine propene, 3-chlorine- 1,2-dihydropropane, trichloropropane, epichlorhydrin, etc.) revealed more frequent than in population spread of osteopenia and osteoporosis. It is shown, that early disturbance of bone metabolism is connected with activation of free-radical oxidation and change of hormonal status in the form of decrease of testosterones and increase of estradiol.
Galimova V.U., Kamilov F.Kh., Gazdalieva L.M., Nuraeva A.B.
INFLUENCE OF SURGERY TREATMENT OF POSTTRAUMATIC EYE PREATROPHY ON THE LEVEL OF NITRIC OXIDE IN BLOOD PLASMA AND LACRIMAL LIQUID
Sotskova V.A., Kamilov F.Kh.
INDEXES OF FREE-RADICAL OXIDATION AND ANTIOXIDANT DEFENSE AS MARKERS OF ADAPTATIVE REACTION OF CHILDREN AT ACTION OF CHEMICAL POLLUTANTS OF ATMOSPHERIC AIR
Correlation of processes of free-radical oxidation and antioxidant defense of children under age of 7-11 years old, living at 3 kilometers zone of chemical, oil-chemical enterprises and heat stations influence is regarded in this article. It is shown that more than one third of children remain in condition of chronic oxidative stress and tension of adaptative processes.
Mamtsev A.N., Bondareva I.A., Kamilov F.H., Kozlov V.N.
ESTIMATION OF PHYSIOLOGICAL ACTIVITY OF IODINE CONTAINING BIOLOGICALLY ACTIVE COMPONENT ON THE BASIS OF PECTIN AT EXPERIMENTAL HYPOTHYROIDISM
In the article the results of researches are submitted according to specific physiological activity of iodine containing organomineral complex in relation to thyroid system of laboratory rats. The importance of chronobiological researches of rats’ body temperature is shown during experimental modeling of hypothyroidism and studying of efficiency of iodine containing biologically active components.
Gazdalieva L.M., Nuraeva A.B., Kamilov F.Kh., Galimova V.U.
LEVEL OF FINAL STABLE METABOLITES OF GOLD OXIDE OF PATIENTS WITH BULLOUS KERATOPATHY
|
|
Editor-in-chief |
Sergey Aleksandrovich
MIROSHNIKOV |
|
|
