2014, № 12 (173)

Pashtayev N.P., Zotov V.V. LOCAL FEMTOCROSSLINKING VERSUS STANDARD CORNEAL COLLAGEN CROSSLINKING IN THE TREATMENT OF PATIENTS WITH PROGRESSIVE KERATOCONUSThere is carried out described comparison and evaluation of clinical and functional results of the local femtoсrosslinking and standard corneal collagen crosslinking (CXL) in patients with progressive keratoconus. 50 eyes of 42 patients with progressive keratoconus stage 2–3 (classified Amsler) were included in clinical follow-up, and were divided into 2 groups of 25 eyes undergoing femtocrosslinking and standard CXL. The observation period was 2 years. Local femtoсrosslinking is safer and more effective treatment of progressive keratoconus that improves functional parameters as well as the standard CXL.Key words: cross-linking of corneal collagen, femtosecond laser, femtocrosslinking.

Download

References:

1. Kennedy, R.H. A 48-year clinical and epidemiological study of keratoconus / R.H. Kennedy, W.M. Bourne, J.A. Dyer // Am. J. Ophthalmol. — 1986. — Vol.101. — P. 267–273.

2. Krachmer, J.H. Keratoconus and related non-inflammatory corneal thinning disorders / J.H. Krachmer, R.S. Feder, M.W. Belin // Surv. Ophthalmol. — 1984. — Vol.28. — P. 293–322.

3. Rabinowitz, Y.S. Keratoconus / Y.S. Rabinovitz // Surv. Ophthalmol. — 1998. — Vol.42. — P. 297–319.

4. Spoerl, E. Untersuchungen zur Verfestigung der Hornhaut am kaninchen / E. Spoerl, J. Schreiber, K. Hellmund // Ophthalmologe. — 2000. — Vol.97. — P. 203–206.

5. Spoerl, E. Erhohung der Festigkeit der Horn haut durch Vernetzung / E. Spoerl, M. Huhle, T. Seiler // Ophthalmologe. — 1997. — Vol.94. — P. 902–906.

6. Wollensak, G. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus / G. Wollensak, E. Spoerl, T. Seiler // Am. J. Ophthalmol. — 2003. — Vol.135. — P. 620–627.

7. Wollensak, G. Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking / G. Wollensak, E. Spoerl, T. Seiler // J. Cataract Refract. Surg. — 2003. — Vol.29. — P. 1780–1785.

8. Keratocyte cytotoxicity of riboflavin/UVA-treatment in vitro / G. Wollensak [et al.] // Eye (Lond). — 2004. — Vol.18. — P. 718–722.

9. Photochemicalkinetics of corneal cross-linking with riboflavin / P. Kamaev [et al.] // Investigative Ophthalmology and Visual Science. — 2012. — Vol. 53. — P. 2360–2367.

10. Wittig-Silva C., Chan E., Islam F. M. A randomized, controlled trial of corneal collagen cross-linking in progressive Keratoconus: three-year results// Ophthalmology.– 2014.-Vol. 121.– P.812–821

11. Faschinger, C. Corneal melting in both eyes after simultaneous corneal cross-linking in a patient with keratoconus and Down syndrome / C. Faschinger, R. Kleinert, A. Wedrich // Ophthalmologe. — 2010. — Vol.107. — P. 951–952.

12. Koller, T. Complication and failure rates after corneal crosslinking / T. Koller, M. Mrochen, T. Seiler // J. Cataract Refract. Surg. — 2009. — Vol.35. — P. 1358–1362.

13. Keratitis and corneal scarring after UVA/riboflavin cross-linking for keratoconus / C. Koppen [et al.] // J. Refract. Surg. — 2009. — Vol. 25. — P. 819–823.

14. Zotov, V.V. New method of corneal collagen cross-linking in treatment patient with keratoconus. Long-term results // Modern technology of bluetongue and refractive surgery: coll. of scien. art. — M., 2011. — P. 299–302.

About this article

Author: Pashtaev N.P.

Year: 2014

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

© Электронное периодическое издание: ВЕСТНИК ОГУ on-line (VESTNIK OSU on-line), ISSN on-line 1814-6465
Зарегистрировано в Федеральной службе по надзору в сфере связи, информационных технологий и массовых коммуникаций
Свидетельство о регистрации СМИ: Эл № ФС77-37678 от 29 сентября 2009 г.
Учредитель: Оренбургский государственный университет (ОГУ)
Главный редактор: С.А. Мирошников
Адрес редакции: 460018, г. Оренбург, проспект Победы, д. 13, к. 2335
Тел./факс: (3532)37-27-78 E-mail: vestnik@mail.osu.ru