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Antonova E.I. INDEXES DYNAMICS OF CELLULAR CYCLE OF AMPHIBIAN HEPATOCYTES OF RANA TERRESTRIS TYPE, INDUCED WITH THERMAL STRESS AS MANIFESTATION OF PRIMARY COMPENSATORY-ADAPTIVE REACTION OF ORGANISM After the influence of hyperthermia on organism of Rana terrestris type amphibian quantitative indexes of hepatocyte DNA repulse primary manifestation of compensatory-adaptive reaction of organism – the level of DNA compaction is increased, the area of chromatin distribution and the area of nucleuses are decreased, metabolic depression is developed at the expense of decrease of hepatocyte number in S- and G2-M-stage of cellular cycle, the part of lost hepatocytes is increased and the activity of cuspaz 3 is increased. The correlation of hepatocytes loss way is 0,8 with predominance of propidiumiodid-positive hepatocytes under hoechst-positive.
About this article
Author: Antonova E.I.
Year: 2008
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Editor-in-chief |
Sergey Aleksandrovich
MIROSHNIKOV |
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