2015, № 12 (187)

Кaiotkina Е.V., Chistyakova S.V., Кuvyrkova O.I. THE RESULTS OF COMPLEX TREATMENT OF OCULAR ISCHEMIC SYNDROMEOcular ischemic syndrome is one of the most difficult to treat pathological conditions of the eye with steadily progressive vision loss and a significant decline in the life quality of patients, especially in the elderly, leading to permanent disability. Often the main background of the disease with ocular ischemic syndrome is a chronic cerebrovascular pathology. In recent years there has been growth in ischemic diseases of the eye, which is associated with the spread of atherosclerosis, hypertension, coronary heart disease, diabetes, and cervical osteochondrosis. The article analyzes the results of complex treatment of patients with ocular ischemic syndrome. Among them were patients with open-angle compensated glaucoma, retinal degeneration, subatrophy of the optic nerve, age-related macular degeneration, nonproliferative diabetic retinopathy. Most patients were chronic cerebrovascular, cardiovascular, bronchopulmonary pathology. The control group received the standard neuroprotectors and angioprotectors, antioxidants and trophic preparations. In the main group in addition to standard treatment was prescribed nasal drops Semax 0,1 % (3 times a day for 20 days). The duration of treatment was 20 days. Treatment courses were repeated every 3–6 months. Comparative evaluation of treatment efficiency was carried out according to visometry and perimetry. In the intranasal use of drops Semax uncorrected visual acuity increased 1.7 times (from 0.18 to 0.32), corrected visual acuity increased 3.1 times (from 0.19 to 0.59). Field of vision increased by 10–15 degrees. Almost all patients of the main group (96 %) reported subjective improvement of vision, improving overall health, mood, increase concentration, improve memory, reduce irritability.Key words: ocular ischemic syndrome, complex treatment.

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References:

1. Baranov V. I., Bereznikov A. I. Differentiated approach to the treatment of partial atrophy of the optic nerve (VAON)// Materials of the VIII all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2009". — M., 2009.

2. Brovkina А.F., Shuko А.G. About differential diagnosis of some types of optic neuropathy // Clinical. Ophthalmology. — 2008. — № 1. — P. 30–33.

3. Danilova L. P., Egorov V. V., Smolyakova G. P., Emanova L. P. Efficacy of comprehensive therapy in the treatment of the neovascular form of age-related macular degeneration// Abstracts of X all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2012". — M., 2012

4. Denisova I. P., Kuznetsov S. L., Brajalovich E. E. To the question about the role of ischemic and involutional factors in the pathogenesis of degenerative eye diseases// Materials of the XII all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2014". — M., 2014

5. Gumowa A. A., Dushin N. V., Frolov M. A., Azibekyan A. B. Modern approach to the treatment of age-related macular degeneration// Abstracts of VIII all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2009". — M., 2009.

6. Zavgorodny Т.S., Sergievskaya L.E., Bezdeneshnay О.А., Bezuglа Е.А. Ocular ischemic syndrome. Modern principles of diagnosis and treatment. — Zaporozhye, 2012. — 248 p.

7. Kasymova M. S. Differentiated approach to the course of anterior ischemic optic neuropathy (AION) of different Genesis// Materials of the VIII all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2009". — M., 2009.

8. Kim S.М. Comprehensive treatment of ocular ischemic syndrome// Materials of VIII Russian scientific and practical. Conf. with international participation "Fedorov reading — 2009". — М., 2009.

9. Kiseleva T. N., Kravchuk E. A. Features of ocular and cerebral blood flow in optic nerve atrophy// Materials of the VIII all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2009". — M., 2009.

10. Makkaeva S.М. Features of ocular ischemic syndrome with dyscirculatory encephalopathy: authoref. dis. ...doctor. med. Sciences — М., 2010. — 53 p.

11. Makkaeva S.М., Ramazanova L.S. The effect of neurometabolic drugs on visual function of patients with chronic ischemic neuropathy // Materials of scientific and practical. Conf. "Pharmacotherapy of diseases of the vision organ". — Kirov, 2009.

12. Mahkamova D. K., Kamilov H. M., Kasymova M. S. Role of impaired neuron-specific protein level in ocular ischemic syndrome// Abstracts of XII all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2014". — M., 2014

13. Morozova L. N., Shamshinova A. M., Stulin I. D. Clinical and functional characteristics of ischemic syndrome of lesions of the visual sensory system in the pathology of the carotid arteries// Materials of the VIII all-Russian scientific-practical. Conf. with international participation "Fedorov readings — 2009". — M., 2009.

14. Tarasova L.N., Kiseleva Т.N., Fokin А.А. Ocular ischemic syndrome. — М.: Medicine, 2003. — 176 p.

15. Chen KJ1, Chen SN, Kao LY, Ho CL, Chen TL, Lai CC, Wu SC. Ocular ischemic syndrome// Chang Gung Medical Journal. 2001 Aug;24(8):483-91.

16. Hazin R1, Daoud YJ, Khan F. Ocular ischemic syndrome: recent trends in medical management// Current Opinion In Ophthalmology. 2009 Nov; 20 (6): 430-3.

17. Mendrinos E1, Machinis TG, Pournaras CJ. Ocular ischemic syndrome// Survey Of Ophthalmology. 2010 Jan-Feb; 55 (1): 2-34.

18. Terelak-Borys B1, Skonieczna K, Grabska-Liberek I. Ocular ischemic syndrome — a systematic review// Med Sci Monit. 2012 Aug; 18 (8):RA138-144.

About this article

Authors: Kayotkina E.V., Kuvyrkova O.I., Chistyakova S.V.

Year: 2015

Editor-in-chief

Sergey Aleksandrovich
MIROSHNIKOV

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