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2015, № 12 (187)



Dashenko K.N. DYNAMICS OF THE FUNCTIONAL PARAMETERS OF THE EYE AND INFLUENCE OF PHENOFIBRATE FOR THEM IN THE EARLY AND LATE PERIODS AFTER COAGULATION OF THE RETINA IN PATIENTS WITH NONPROLIFERATIVE DIABETIC RETINOPATHYThe main treatment for diabetic retinopathy is laser photocoagulation of the retina that allows you to save the vision in more than 80 % of cases. However, the influence of laser treatment on electrophysiological parameters of the eye in the early and late periods after taking of phenofibrate studied enough. We investigated the prospective and retrospective groups. All patients had nonproliferative stage of the DR with the risk of proliferation. He was executed laser coagulation of the retina. Part patients received fenofibrate (tricor), others do not. In the prospective group assessed the volatility nekorregirovannyh and korregirovannoe visual acuity and electrophysiological parameters of the eye. Laser coagulation of the retina in a small volume in patients with nonproliferative DR as soon as possible contributes to the stabilization of visual acuity and even a slight increase. After the laser treatment of all electrophysiological parameters significantly increased the latency of the ERG waves. To a lesser extent, the latency was increased in patients treated with fenofibrate. In the retrospective group explored the dynamics nekorregirovannyh and korregirovannoe visual acuity. In the group of patients not receiving fenofibrate, visual acuity after 3 months after laser treatment gradually decreased by 3–5 years: 31,4 % nekorregirovannyh and 28 % korregirovannye from initial values. In the group of patients treated with fenofibrate visual acuity gradually decreased from 1 year to 3–5 years has decreased by 26,3 % nekorregirovannyh and 11 % korregirovannye. Laser coagulation of the retina in patients with nonproliferative stage of the DR in the coming time causes an increase of the latency of ERG, indicating some inhibition of electrogenesis of the retina. The appointment of fenofibrate (tricor) helps to minimize the negative effects of laser photocoagulation on the retina as in the next, and in the long-term along with the compensation of the general condition.Key words: diabetic retinopathy, laser coagulation of a retina, phenofibrate.

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About this article

Author: Dashenko K.N.

Year: 2015


Editor-in-chief
Sergey Aleksandrovich
MIROSHNIKOV

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