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March 2015, № 3 (178)



Shilin V.A., Safronov A.A., Kozhanova T.G. STIMULATION OF REPARATIVE OSTEOGENESIS IN PSEUDOARTHROSIS IN THE EXPERIMENT IN RATSPseudoarthrosis are observed in 16–40 % of cases of long bones fractures. This pathology is observed in young adults. Applied surgical techniques are characterized by a high percentage of failures. The using of hydroxyapatite-collagen complex "Litar" in the experiment on rats showed its high effectiveness in stimulation of reparative osteogenesis. Immunohistochemical method was developed to quantify the proliferative activity of osteoblasts in the experiment compared to the control group. The use of "Litar" increases the processes of osteogenesis. The mechanism is associated with increased activity of blasts cells and stimulation of angiogenesis.Key words: stimulation of osteogenesis, pseudoarthrosis, "LitAr", hydroxyapatite.

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References:

1. Barabash A.P. Scientific and practical contribution of employees of SARNIITO to a technique of a chreskostny osteosynthesis//Saratov scientific and medical magazine. 2011. T. 7, No. 2. Page 502-505.

2. Bauer I.W. Organizational technology factors of emergence of complications at fractures of bones and problems of treatment of heavy damages of the musculoskeletal device / Bauer I.V., Kazarezov M. V., the Queen A.M. and B''day//the VII Congress of traumatologists-orthopedists of Russia — Novosibirsk, 2002 — C 26-27.

3. Berchenko of G. N. Sinteticheskiye calcium-fofsatnye materials in traumatology and orthopedics / G. N. Berchenko//Sb. works of the All-Russian scientific and practical conference. Use of artificial calcium-phosphatic biomaterials in traumatology and orthopedics. — Moscow, 2010. — Page 3-5.

4. Gololobov V. G Posttravmaticheskaya regeneration. In a kn:rukovodstvo on histology. — T.1. — SPb.: Speciallitas. — 2001. — Page 328-334.

5. Lavrishcheva G. I., Onopriyenko G. A. Morphological and clinical aspects of reparativny regeneration of basic bodies and fabrics. — Moscow: Meditsin, 1996. — 208s.

6. Litvinov S. D. Prospects of use of the material "Litar" for restoration of a cartilaginous partition of a nose at Children / Litvinov S.D., Seryogin A.S., Pushtova T.B., Oleynikova M. M.//Russian otorhinolaryngology. 2006. No. 3. Page 66-70.

7. Litvinov S. D. The nanodimensional composite material "Litar" — a universal implant. Samara, 2008. — 250 pages.

8. Onopriyenko G. A. Clinical aspects of microcirculation and regeneration of a bone tissue//Actual problems of medicine.-1993. — Page 41-44

9. Hernigou P., Beau jean F. Bone marrow in patients with pseudarthrosis. A study of progenitor cells by in vitro cloning // Rev. Chir. Orhop.- 1997.- Vol.83, №1. P.33-40.

10. Peterson B., Whang P.G., Iglesias R., Wang J.C., Lieberman J.R. Osteoinductivity of commercially available demineralized bone matrix. Preparations in a spine fusion model // J. Bone Joint Surg. Am. — 2004. — V.86. — №10. — P. 2243-2250.

11. Roach J.W., Shindell R., Green N.E. Late-onset pseudarthrosis of the dysplastic tibia // J. Bone Jt Surg. (Am.).- 1993,- Vol.75, №11.- P.1593-1601.

12. Tay W.H., de Steiger R., Richardson M., Gruen R., Balogh Z.J. Health outcomes of delayed union and nonunion of femoral and tibial shaft fractures // Injury. — 2014. — V.45. — №10. — P. 1653-1658.


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Year: 2015


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