Panova I.E., Zhiliaeva О.V., Shaimov T.B., Abdulaeva E.A.
COURSE OF CHOROIDAL NEOVASCULARIZATION IN PATIENTS WITH NEOVASCULAR STAGE AGE-MACULAR DEGENERATION AND AXIAL MYOPIA ON THE BACKGROUND OF ANTI-VEGF THERAPY ^{[№ 12 ' 2015]}
The current age-related macular degeneration (AMD) and axial myopia (OM) may be accompanied by development of choroidal neovascularization (CNV), which leads to in permanent decrease of visual functions in patients. The combination of AMD and OM in clinical practice not uncommon which complicates the disease. Anti-VEGF therapy is a drug therapy CNV resolution in the Russian Federation. Comparative analysis of the parameters of optical coherence tomography (OCT) and data visometry in 37 patients (40 eyes) with neovascular stage age-related macular degeneration (AMD), and 23 patients (26 eyes) with AMD, occurring against the backdrop of axial myopia who received treatment intravitreal injections ranibizumab to clinical stabilization process in the study conducted. Mostly occult choroidal neovascularization occurred in both treatment groups. Positive results were obtained in both groups: the maximum increase in visual acuity occurred after the fourth injection, improvements in OCT — after the first injection. The best therapeutic response in a fit of the retinal pigment epithelium detachment in patients diagnosed with AMD, while the best performance in the treatment of comorbidity achieved a reduction of neuroepithelial detachment and cystoid changes of retinal.