Bykova E., Sogolovskaya E., Sotnikova T., Gabriel T.
ANALYSIS OF CHANGES IN THE FACTORS OF NONSPECIFIC PROTECTION OF BIOLOGICAL FLUIDS IN VIRAL LESIONS OF THE EYES SURFACE ^{[№ 12 ' 2015]}
It is known that in adenoviral conjunctivitis, herpes and other infectious diseases in the human body increases the production of specific and nonspecific protection factors. Nonspecific factors include lysozyme (muramidase) and ceruloplasmin, which form together with other factors, antibacterial, antiviral and antiradical body protection (ABP, AVP, ARP). Adenoviral infection first develops in the nasopharynx, and then raises along tear duct, and involves in the pathological process the conjunctiva and lacrimal apparatus of the eye. The virus of herpes resides in the human body in a latent state and, periodically sharpening, causes ophthalmic herpes. Individual drugs used in ophthalmology for the treatment of viral infections (adenoviral keratoconjunctivitis and ophthalmic herpes), have the ability to inhibit the lysozyme activity (e.g., cycloferon, interferon and poludan). The enzyme activity of ceruloplasmin depends on the chemical structure of a drug and additionally introduced ingredients.