Shchepitova N.E., Sycheva M.V., Kartashova O.L.
SCRINNING OF ENTEROCOCCUS CULTURE TO CREATE PREPORATION OF PROBIOTIC ACTION ^{[№ 13 ' 2015]}
In the conditions of fight against an antibiotic resistance of microorganisms search of antimicrobic means alternative to traditional antibiotics is of particular importance. Bacteriocins of enterococci can form a basis for new antimicrobic preparations. In this regard screening of new safe strains producers of enterococci for receiving bacteriocins is the actual and perspective direction of modern microbiology. In the specific analysis of bacteria of the genus Enterococcus, defined from intestines of different animals species. In population of faecal enterococci the wide popularity of antagonistic activity regarding bacterias Listeria spp. and Enterococcus spp. which is correlative to the genes of bacteriocinogenia. On the model of experimental infection shows the use the protection effect of listerios defence by antoganistically active enterococci of intestines nature. On the basis of a complex assessment of phenotypic and genetic characteristics of enterococci isolated from intestines of healthy animals is selected strain Enterococcus faecium which is possessing genetic determinants of bacteriocinogenia, the expressed antagonistic effect against Listeria and not having virulence factors.