Panova I.E., Zhiliaeva О.V., Shaimov T.B., Abdulaeva E.A.
COURSE OF CHOROIDAL NEOVASCULARIZATION IN PATIENTS WITH NEOVASCULAR STAGE AGE-MACULAR DEGENERATION AND AXIAL MYOPIA ON THE BACKGROUND OF ANTI-VEGF THERAPY ^{[№ 12 ' 2015]}
The current age-related macular degeneration (AMD) and axial myopia (OM) may be accompanied by development of choroidal neovascularization (CNV), which leads to in permanent decrease of visual functions in patients. The combination of AMD and OM in clinical practice not uncommon which complicates the disease. Anti-VEGF therapy is a drug therapy CNV resolution in the Russian Federation. Comparative analysis of the parameters of optical coherence tomography (OCT) and data visometry in 37 patients (40 eyes) with neovascular stage age-related macular degeneration (AMD), and 23 patients (26 eyes) with AMD, occurring against the backdrop of axial myopia who received treatment intravitreal injections ranibizumab to clinical stabilization process in the study conducted. Mostly occult choroidal neovascularization occurred in both treatment groups. Positive results were obtained in both groups: the maximum increase in visual acuity occurred after the fourth injection, improvements in OCT — after the first injection. The best therapeutic response in a fit of the retinal pigment epithelium detachment in patients diagnosed with AMD, while the best performance in the treatment of comorbidity achieved a reduction of neuroepithelial detachment and cystoid changes of retinal.

Panova I.E., Shaimov T.B., Abdullaeva E.A.
CLINICAL ASPECTS OF A POLIPOIDNY HORIOIDALNY VASKULOPATIYA AS ATYPICAL OPTION OF A CURRENT OF A NEOVASCULAR FORM OF AGE MAKULYARNY DYSTROPHY ^{[№ 12 ' 2015]}
The problem of a neovascular form of the age makulyarny dystrophy (AMD) has special value in connection with the high frequency of an invalidization from this disease. An atypical form of neovascular process is the polipoidny horioidalny vaskulopatiya (PHV), the etiology and which pathogenesis aren't up to the end studied. The current of PHV is characterized by anevrizmalny expansions on the terminations of the branching network from abnormal the horioidalnykh of vessels, antiangiogenny methods of treatment of this disease not always have desirable efficiency. Therefore it is important to reveal a polipoidny horioidalny vaskulopatiya among patients with "damp" age makulyarny dystrophy. The main oftalmoskopichesky signs of a polipoidny horioidalny vaskulopatiya on the basis of the comparative analysis with the classical and hidden neovaskulyarization forms at VMD are studied. The following differences from typical forms of a neovaskulyarization at age makulyarny dystrophy are revealed: rare presence Druze (54.0 %), parafovealny localization of an otsloyka of a neurotouch retina (56.0 %), perifovealny localization of an otsloyka of a pigmentary epithelium (26.0 %), kistovidny hypostasis of a retina (48.0 %), and also existence of gemorragiya (56.0 %) mainly subretinalnykh (48.0 %) and solid exudate (82 %). Occurrence frequency the subretinalnykh of red-orange small knots as specific sign of PHV made 90 %. The main triad clinical the oftalmoskopicheskikh of signs of a polipoidny horioidalny vaskulopatiya at patients with age makulyarny dystrophy is revealed: rare presence Druze, solid "honey" exudate, red-orange subretinalny small knots. The obtained data should be considered in clinical diagnostics of a polipoidny horioidalny vaskulopatiya at patients with a neovascular form age makulyarny dystrophy.

Shaimova T.A., Panova I.E., Ermak E.M.
OCT-PARAMETERS OF CHORIORETINAL COMPLEX IN PATIENTS WITH COMBINED PATHOLOGY — AGE-RELATED MACULAR DEGENERATION AND PRIMARY OPEN ANGLE GLAUCOMA ^{[№ 12 ' 2015]}
Age-related macular degeneration (AMD), and primary open angle glaucoma (POAG) — the main reasons for the decrease of visual function and quality of life in older age and advanced age patients. The purpose of this study is to identify the OCT-parameters features of chorioretinal complex in patients with combined pathology — the dry form of AMD and POAG. There were 98 patients (192 eyes), we identified three study groups (SG): SG1 — AMD with POAG — 63 eyes; SG2 — AMD without neuroopticopathy — 56 eyes, SG3 — POAG without AMD — 40 eyes; the average age — 75.7 ± 6.5 years. Manually measure of the neuro-sensory retina (NSR) thickness, the ganglion cells complex (GCC) thickness and the choroid thickness by optical coherence tomography were performed in two areas: 4 mm lateral (area I) and 4 mm medial (area II) to the optic nerve head. Index of GCC thickness (GCCT) was calculated equal to the ratio: GCC thickness/ NSR thickness. It was found that in patients with combined pathology — AMD and POAG (SG1) thickness of the NSR, thickness of the GCC, index of GCCT and choroid thickness significantly reduced in the area I and II in comparison with the control group. In the patients of SG1 NSR thickness, GCC thickness, index of GCCT was significantly lower in area I and II; choroidal thickness was lower in the area I and significantly lower in area II in comparison with patients of SG2. The research results of OCT-parameters of chorioretinal complex in patients with combined pathology (AMD and POAG) determined the severity of progressive course of AMD in patients with POAG predominance of atrophic form.