Musina L.A., Nuraeva A.B.
BURN WOUND HEALING WHEN USING ALLOGENIC BIOMATERIALS (EXPERIMENTAL STUDY) ^{[№ 12 ' 2015]}
Prevention of eyelid cicatricial deformity secondary to trauma or burn is the unmet need in ophthalmosurgery. In order to understand the mechanisms of tissue regeneration after eyelid surgical repair using allogenic biomaterials it is interesting to compare burn wound healing process without treatment, using conventional medications (Actovegin) and with the use of allogenic biomaterials in experiment. In the experiment was conducted on 84 white Wistar male-rats. Heat injury was modeled. In control group without treatment the healing process was accompanied by prolonged eschar presence, late epithelisation and slowdown of newly formed connective tissue maturation due to marked inflammation process. Reparation was incomplete and accompanied by coarse scarring. In the second control group treated with Actovegin the epithelisation was faster, nevertheless slowdown of reparation process in dermal layer was noticed. Inflammatory processes prevailed over reparative ones, granulation tissue stayed immature for a long time and eventually underwent scarring. In treatment group where animals underwent subcutaneous injection of disperse biomaterials (made from derma and tendon) rapid proliferation of epithelium was noted as long as necrotic mass demarcation and fast eschar desquamation. As granulation tissue matured it formed proper connective tissue plate of skin. It was found that the use of allogenic biomaterials in skin burns accelerated epithelisation and leaded to complete defect closure. Biomaterials inhibit coarse scarring during healing process.

Shangina O.R., Musina L.A.
ELASTIC-DEFORMATIVE PROPERTIES OF COMBINED ALLOGRAFTS FOR THE RESTORATION OF THE ORBITAL WALLS ^{[№ 12 ' 2015]}
The necessity of studying biomechanical properties of allografts stems from the inquiries of practical medicine. Problems of restoration surgery, transplantology and other sciences are solved based on the study of strength and deformative properties of tissues. The aim of physico-mechanical investigations is the evaluation of allograft as the material which temporary or constantly performs mechanical functions following the transplantation. Different methods of manufacture, preservation, lyophilization and sterilization of allografts lead, on frequent occasions, to the changes of biomechanical properties. The conservation of elastic-deformative properties of allografts during the process of their manufacture is an important factor which sets conditions for the effect of their clinical practice. Biomechanical tests were carried out in the tissue bank of the Russian Eye and Plastic Surgery Centre to evaluate strength properties of combined allografts manufactured according to Alloplant technology for the restoration of orbital walls. Combined allografts were modeled from the derma of the foot supporting areas and then were reinforced by the costal cartilage. The carried out tests showed the following results — the parameters of relative elongation, ultimate strength and Young's modulus of elasticity of derma allografts didn't subject to reliable changes (compared with the control group — native derma). It allows to make a conclusion that mechanical properties of the given allografts are preserved after the physico-chemical treatment. Ultimate strength and plastic deformation parameters of the allografts reinforced by the costal cartilage treated as per Alloplant technology didn't undergo considerable changes as well, compared with the control group (native derma). It is established that multistage physico-chemical treatment as per Alloplant technology does not have an adverse effect on the strength characteristics of the derma of the foot supporting areas and costal cartilage which are used to manufacture a combined allograft for the restoration of the orbital walls. Such strength properties of allografts as tension and deformation, which in their turn, are of the utmost significance play an important part in reconstructive surgeries.

Semenova I.N., Kuzhina G.Sh., Seregina Y.Y., Yagafarova G.A., Zulkarnaev A.B., Musin Kh.G.
USE OF PLANT TEST SYSTEMS TO ASSESS THE TOXICITY OF BOTTOM SEDIMENTS ^{[№ 10 ' 2015]}
This article is devoted to research the variability of heavy metals (Cu, Zn, Fe, Cd, Pb, Co, Ni, Mn) in sediments of r. Belaja on the territory of the Republic of Bashkortostan of Beloretsk district. The study of metals in their average content in the sediment form the following decreasing number of elements: Fe>Mn> Zn> Ni> Cu>Pb> Co> Cd. The concentration of Cu, Zn, Cd, Fe, Ni, Co in the sediments of the river exceeded the value of background: сopper — in the 6–15 times, zinc — in the 13–20 times, cadmium — in the 10–13 times, nickel — in the 1.5 times, iron — in the 9–11 times, cobalt — in the 155–185 times, lead — in the 1.6 times. The concentration of manganese in all soils studied watercourse was within the geochemical background. Total index of contamination ranged from 201 to 243. The evaluation of the toxicity of the river sediments were determined by bioassay using the seeds of Lepidium sativum L., Raphanus sativus L., Triticum aestivum L. Learned test systems according to the degree of sensitivity can be arranged in the following decreasing series: Lepidium sativum L. > Raphanus sativus L. > Triticum aestivum L. The greatest sensitivity to contamination had such a test responses as seed germination and seedling root length. In this paper, the connection between the content of heavy metals in bottom sediments exceeding the geochemical background, and a manifestation of the properties of the indicator: increase in the concentration of copper and nickel inhibits seed germination, root length, and seedling dry weight of the plant model. The use of these plant test systems allowed to conclude that the studied soils of r. Belaja are moderately toxic pollution degree, except for the alignment after the confluence r. Tirlyan characterized by narrow riverbed and, as a consequence, increase the speed of its flow with a predominance of the processes leaching of toxic elements from the sediments.

Suhova V., Kolinichenko O., Starkov I., Starkova M., Vdovenko E., Gumirov I., Musin A.
SCIENTIFIC-TECHNICAL PROGRESS AND SCIENTIFIC-ENGINEERING PROBLEMS OF INDUSTRIAL SAFETY ^{[№ 9 ' 2015]}
It is shown that to ensure the safety and viability of the planet's growing population requires not only a constant increase in resources, but also to avoid the risks associated with the use of scientific and technological progress. Start of civilized management of hazardous industrial processes and facilities in the country was initiated adoption of the Federal Law № 116-FL of 21.07.1997 (12.21.2014), where the main requirements for industrial safety. For example of the Orenburg gas complex, the possible risks at hazardous production facilities at the impact of natural character illustrated. Industrial safety as an area of scientific activity is regarded. The basic stages of its development and improvement, including mathematical methods and computer technology risk prediction, identification of the causes of disasters, the development of new diagnostic tools and technical methods to assess the mechanics of deformation and fracture.

Musina L.А., Khismatullina Z.R., Balkhiyeva L.Kh., Baygildin S.S., Vakhitova E.A.
CHARACTERISTIC PROPERTIES OF THE EYE RETINAL RADIAL GLIOCYTES OF EXPERIMENTAL RATS WITH PIGMENTED DEGENERATION ^{[№ 12 ' 2014]}
It was established that eye retinal radial gliocytes of WAG/Rij experimental rats with differences of genotype as per Tag 1A locus of DRD2 are characterized by destructive and proliferative changes accompanied by the expression of various degree of GFAP acidic glial fibrillar protein.

Shangina O.R., Musina L.А., Gaynutdinova R.D., Bulgakova L.A
EXPERIMENTAL AND MORPHOLOGICAL SUBSTANTIATION OF THE USE OF LASER RADIATION IN MODELING THE GRAFTS FOR OPHTHALMOSURGERY ^{[№ 12 ' 2014]}
There was carried out and experimental and morphological investigation of allografts for ophthalmosurgery modeled by laser radiation. It was established that modeling with laser cutting mode selection and peculiarities of the graft fibroarchitectonics taken into account allows to make the most of retaining their structure and it doesn't have a negative effect on the process of substitution and regeneration of tissues in grafting.

Musina L.A., Muslimov S.A., Kornilaeva G.G., Solovyeva E.P., Kornilaeva M.P.
THE MORPHOLOGY OF SPONGE ALLOGRAFT IN THE LONG-TERM PERIOD FOLLOWING THE ANTIGLAUCOMATOUS SURGERY ^{[№ 4 ' 2013]}
The enucleated eye balls of four patients who earlier underwent antiglaucomatous surgery using a sponge allograft have been investigated by histologic and electron-microscopic methods. It was revealed that in the long-term period (up to 8 years) following the surgery there had been detected the tissue on the place of the allograft similar to the eye trabecular meshwork structure maintaining drainage properties.

Muhsinova L.H., Musina G.R.
KEY AREAS OF INNOVATION IN OIL PRODUCTION UNDER RUSSIA'S ENTRY INTO WTO ^{[№ 13 ' 2012]}
In this paper the following issues are grounded: development of the national strategy for monitoring the activities of oil industry, strengthening of the state regulatory role in the field of enhanced oil recovery, creation of high-tech innovative oilfield service companies and oilfield engineering in partnership with the state.

Musina L.А., Balkhiyeva L.Kh., Khismatullina Z.R., Tabanakova Т.М.
THE EXPERIMENTAL MODEL OF THE EYE RETINAL PIGMENTAL DEGENERATION ^{[№ 12 ' 2012]}
The pigmental epithelial cell structure of WAG/Rij rat strain retina has been studied with histological and electron-microscope methods. A new potentially useful experimental model was recommended to develop the methods for the treatment of the eye retinal degenerative diseases.

Shcherbakov D.A., Nuraeva A.B., Musina L.M.
INFERIOR ORBIT WALL RECOVERY USING CHONDRAL ALLOGRAFTS ^{[№ 12 ' 2012]}
We have proved experimentally what the feasibility of chondral allografts for reimbursement of various defects of the inferior orbit wall. In the clinical part of the study we have developed indications for plate chondral allograft for fractures of the inferior orbital wall type blow-out with prolapse of orbital contents into the maxillary sinus and the combination of connective biomaterials to reconstruct small defects of the inferior orbital wall.

Kashin V.V., Musin D.Z.
RICHARD RORTY: CRITISISM OF PHILOSOPHY AS A REPRESENTATION ^{[№ 7 ' 2012]}
In the 20th century a number of attempts were done to lead a "reconstruction" of the history of philosophy to modern realities. One of these attempts was made by a famous American philosopher, representative of neopragmatism, Virginia University professor Richard Rorty. His "reconstruction" was to substitute epistemology by literary criticism.

Kashin V.V., Musin D.Z.
CHARLES PEIRCE ON REPRESENTING FUNCTION OF THE SIGN ^{[№ 7 ' 2010]}
Pragmatism relies upon "prescription" and availability of its objects in primary source, as well as upon separation of knowledge object and subject. Transparency or unshadiness from the point of view of reference of relations between subject and object and serves as one of the grounds for possibility of undistorted presentation of reality. Knowledge results "truth test" is performed by means of returning to this "prescription" with the help of relevant methods. Pragmatism assumes that though cogitation is based on presentation, "nothing stands" between consciousness and object: constantly improved methods allow to correlate representation and presentation through relations "truth — false".

Bulatov R.T., Galimova V.U., Musina L.A., Rodionov O.V.
EXPERIMENTAL SCLEROPLASTY WITH TENDINOUS-FASCIAL ALLOGRAFT ^{[№ 12 ' 2007]}

Bulatov R.T., Galimova V.U., Rodionov O.V., Musina L.A.
MORPHOLOGICAL RESEARCHES ANALYSIS OF BIOPTIC MATERIAL FRAGMENTS OF DIFFERENT ALLOGRAFTS AFTER SCLEROPLASTY ^{[№ 12 ' 2007]}

Bulatov R.T., Galimova V.U., Rodionov O.V., Musina L.A.
EXPERIMENTAL SCLEROPLASTY WITH ALLOGRAFT OF TESTICLE ALBUGINEA ^{[№ 12 ' 2007]}